NCT05905809 (UNIBRACE) is a NA clinical trial of UniRelieverTM offloading brace (THUASNE) in Osteoarthritis, Knee, sponsored by Thuasne.

Who is sponsoring NCT05905809?

NCT05905809 is sponsored by Thuasne.

What drugs are being tested in NCT05905809?

Interventions in NCT05905809: UniRelieverTM offloading brace (THUASNE), Unloader One® X brace (Össur).

What condition does NCT05905809 study?

NCT05905809 studies Osteoarthritis, Knee.

Is NCT05905809 still recruiting?

NCT05905809 is currently completed. Last updated 17 April 2024.

Last reviewed 2024-04-17 · How we verify

NCT05905809: UNIBRACE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of UniRelieverTM Offloading Brace in the Management of Knee Osteoarthritis

Completed NA Last updated 17 April 2024

What this trial tests

NA trial testing UniRelieverTM offloading brace (THUASNE) in Osteoarthritis, Knee in 60 participants. Completed in 20 September 2023.

Timeline

7 June 2023

Primary endpoint
20 September 2023

20 September 2023

Quick facts

Lead sponsor	Thuasne
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	60
Start date	7 June 2023
Primary completion	20 September 2023
Estimated completion	20 September 2023
Sites	1 location across Germany

Drugs / interventions tested

UniRelieverTM offloading brace (THUASNE)
Unloader One® X brace (Össur)

Conditions studied

Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →

Sponsor

Thuasne

Who can join

18 and older, any sex, with Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study is to assess the efficacy and performance of a new semi-rigid offloading brace in the management of knee osteoarthritis.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The effectiveness of the UniReliever offloading knee brace for treating medial knee osteoarthritis: A randomized clinical trial.
Benning M, Villet S, Marques A, Hilgers RD. · · 2025 · PMID 41331771 · DOI 10.1097/pxr.0000000000000503

Verify or expand the search:

Other recruiting trials for Osteoarthritis, Knee

Currently open trials in the same condition.

NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting

Other Thuasne trials

Trials by the same sponsor.

NCT07125092 — A Study to Evaluate the Clinical Benefit and Safety of Medical Compression Garments in the Management of Patients With L · NA · not yet recruiting
NCT06264817 — Auto-Adjustable MOBIDERm Autofit Armsleeve in the Management of Upper Limb Lymphedema. · NA · recruiting
NCT05716165 — Effect of Proprioceptive Knee Braces on the Performance and Endurance of Recreational Soccer Players Aged 60-80 Years · NA · completed
NCT05435040 — Evaluation of Proprioceptive Abilities While Wearing an Elastic Orthosis in Patients With Proprioceptive Knee Deficits · NA · completed
NCT05600543 — Evaluation of the Effect of Lumbar Belt on Spinal Mobility in Subjects With and Without Low Back Pain · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05905809 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Thuasne
Last refreshed: 17 April 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05905809.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing