NCT05903222 (PALACS-EF) is a clinical trial of Non-Interventional in Atrial Fibrillation, sponsored by Weill Medical College of Cornell University.

Who is sponsoring NCT05903222?

NCT05903222 is sponsored by Weill Medical College of Cornell University.

What drugs are being tested in NCT05903222?

Interventions in NCT05903222: Non-Interventional.

What condition does NCT05903222 study?

NCT05903222 studies Atrial Fibrillation.

Is NCT05903222 still recruiting?

NCT05903222 is currently completed. Last updated 29 January 2025.

Last reviewed 2025-01-29 · How we verify

NCT05903222: PALACS-EF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery-Extended Follow-Up

Completed Last updated 29 January 2025

What this trial tests

trial testing Non-Interventional in Atrial Fibrillation in 420 participants. Completed in 13 October 2024.

Timeline

1 July 2022

Primary endpoint
26 September 2024

13 October 2024

Quick facts

Lead sponsor	Weill Medical College of Cornell University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	420
Start date	1 July 2022
Primary completion	26 September 2024
Estimated completion	13 October 2024
Sites	1 location across United States

Drugs / interventions tested

Non-Interventional

Conditions studied

Atrial Fibrillation — all drugs for Atrial Fibrillation →

Sponsor

Weill Medical College of Cornell University

Who can join

18 and older, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of the Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery (PALACS, NCT02875405) trial was to determine if performing posterior left pericardiotomy at the time of cardiac surgery prevents atrial fibrillation after cardiac surgery. The purpose of the Posterior left pericardiotomy for the prevention of AtriaL fibrillation After Cardiac Surgery-Extended Follow-Up (PALACS-EF) study is to evaluate the effect of posterior left pericardiotomy on 5-year clinical outcomes.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Drainology: Leveraging research in chest-drain management to enhance recovery after cardiothoracic surgery.
Lobdell KW, Perrault LP, Drgastin RH, Brunelli A, et al · · 2024 · cited 6× · PMID 38899104 · DOI 10.1016/j.xjtc.2024.04.001
The Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery-Extended Follow-Up study (PALACS-EF): rationale and design.
Gaudino M, Harik L, Redfors B, Sandner S, et al · · 2023 · cited 1× · PMID 38035038 · DOI 10.1093/ehjopen/oead118

Verify or expand the search:

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Other recruiting trials for Atrial Fibrillation

Currently open trials in the same condition.

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Other Weill Medical College of Cornell University trials

Trials by the same sponsor.

NCT07485712 — Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2 · NA · not yet recruiting
NCT05811338 — Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 1 · NA · not yet recruiting
NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
NCT06818734 — Implementation of a Clinical Decision Support Tool for Postpartum Depression · NA · not yet recruiting
NCT07485725 — Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 3 · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05903222 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Weill Medical College of Cornell University
Last refreshed: 29 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05903222.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing