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NCT05898191
Effect of Laser Therapy on Vaginal Tissue
NA trial testing vaginal laser treatment in Pelvic Floor Disorders in 15 participants. Status unknown.
1 March 2024
Quick facts
| Lead sponsor | Institute for the Care of Mother and Child, Prague, Czech Republic |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 15 |
| Start date | 1 February 2019 |
| Primary completion | 1 March 2024 |
| Estimated completion | 1 March 2024 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- vaginal laser treatment
Conditions studied
- Pelvic Floor Disorders — all drugs for Pelvic Floor Disorders →
- Vaginal Atrophy — all drugs for Vaginal Atrophy →
Sponsor
Institute for the Care of Mother and Child, Prague, Czech Republic
Who can join
Eligibility, female only, with Pelvic Floor Disorders or Vaginal Atrophy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pelvic floor disorders, including prolapse, incontinence, and vulvovaginal atrophy decrease the quality of life of every fourth woman. Recent therapy including habits change, rehabilitation, surgery, or hormonal replacement is not possible in all patients. Laser therapy is currently being proposed as an alternative. Laser therapy was brought to the gynecological field from dermatology, where it is used for facial rejuvenation (wrinkles) and treatment of other skin abnormalities. In dermatology, the laser has proven its efficacy at the molecular and histological levels. However, this concept was brought to gynecology without comparable confirmation. The skin and vagina have a different structures, therefore effects of laser may differ. Patient satisfaction with the clinical effects of laser has been reported. However, based on recent reviews and sheep studies knowledge about histological and other effects is limited. The goal of this study is to gain knowledge about the histological, biomechanical effects and molecular effects of laser on vagina. Control samples were collected from women undergoing colporrhaphy. The laser group underwent laser treatment prior to the surgery. The gained knowledge may improve laser protocols and in the future maybe laser therapy will become standard treatment in urogynecology.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05898191
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Pelvic Floor Disorders
Currently open trials in the same condition.
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- NCT06796985 — Botox for Chronic Pelvic Pain · Phase 1 · recruiting
- NCT06808542 — Pelvic Floor Dysfunction Among Female Physiotherapy Students: A Cross-Sectional Study · recruiting
Other Institute for the Care of Mother and Child, Prague, Czech Republic trials
Trials by the same sponsor.
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- NCT05801523 — Laparoscopic Therapy of Endometrioma: Sclerotherapy vs Cystectomy in Patients With Unfinished Reproductive Plans · NA · recruiting
- NCT04671914 — Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester. · Phase 4 · recruiting
- NCT05800678 — Cross-sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05898191 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Institute for the Care of Mother and Child, Prague, Czech Republic
- Last refreshed: 5 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05898191.
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