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Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester. (ADAB)
Only patients who sign an informed consent will be included. Patients after a miscarriage in the 2nd trimester of pregnancy who need to perform an instrumental revision of the uterine cavity (RCUI, revisio cavi uteri instrumentalis) will be randomized into two groups. In the first group, RCUI will be performed according to current standards. In the second group, an anti-adhesive preparation with hyaluronic acid (Hyalobarrier gel Endo) will be applied to the uterine cavity at the end of the RCUI procedure. Eight to twelve weeks after the operation, the occurrence of adhesions will be evaluated by ultrasound examination and diagnostic hysteroscopy (if adhesions will be detected, they will be disrupted). The study will also include the completion of a questionnaire in terms of the frequency and strength of the menstrual cycle. The presence of adhesions will be assessed according to The American Fertility Society (AFS).
Details
| Lead sponsor | Institute for the Care of Mother and Child, Prague, Czech Republic |
|---|---|
| Phase | PHASE4 |
| Status | RECRUITING |
| Enrolment | 200 |
| Start date | Tue Sep 28 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Apr 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Asherman Syndrome
- Abortion Late
Interventions
- Hyaluronic Acid 20 MG/ML Injectable Solution
- Dilation and curretage
Countries
Czechia