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NCT05878249
Role Of Wound Lavage in Direct Pulp Capping Of Permanent Teeth With Carious Exposure
NA trial testing wound lavage with normal saline in Reversible Pulpitis in 140 participants. Status unknown.
30 April 2024
Quick facts
| Lead sponsor | Postgraduate Institute of Dental Sciences Rohtak |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 140 |
| Start date | 1 November 2022 |
| Primary completion | 30 April 2024 |
| Estimated completion | 31 May 2024 |
| Sites | 1 location across India |
Drugs / interventions tested
- wound lavage with normal saline
- wound lavage with sodium hypochlorite
- wound lavage with Ethylenediaminetetraacetic acid(EDTA)
- wound lavage with sodium hypochlorite followed by Ethylenediaminetetraacetic acid
Conditions studied
- Reversible Pulpitis — all drugs for Reversible Pulpitis →
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Who can join
Adults 18 to 50, any sex, with Reversible Pulpitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
the purpose of the study is to investigate the outcome of wound lavage agents Sodium hypochlorite and Ethylenediaminetetraacetic acid (EDTA) in direct pulp capping of mature permanent teeth with carious exposure.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of sodium hypochlorite and edta lavage on success rates and postoperative pain in direct pulp capping of cariously exposed permanent teeth: a randomised controlled trial : Corresponding author.
Singh A, Mittal S, Tewari S, Duhan J, et al · · 2025 · PMID 41417101 · DOI 10.1007/s00784-025-06706-6
Verify or expand the search:
- PubMed search for NCT05878249
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Reversible Pulpitis
Currently open trials in the same condition.
- NCT07073573 — Evaluation of Pulpal Biomarkers in Vital Pulp Therapy · NA · active not recruiting
- NCT07391124 — In Vivo Pulp Thermal Changes During Different Slenderization Techniques · NA · active not recruiting
- NCT06844448 — The Effect of Different Risk Factors on the Success Rate of VPT · recruiting
- NCT06433297 — Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars · NA · recruiting
- NCT07101068 — Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syrin · NA · recruiting
Other Postgraduate Institute of Dental Sciences Rohtak trials
Trials by the same sponsor.
- NCT07412067 — Healing of Apicomarginal Defects Using Autograft or Allograft With Collagen Membrane · NA · not yet recruiting
- NCT07381595 — Role of Subgingival Instrumentation in Oral Lichen Planus · NA · not yet recruiting
- NCT07300124 — Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis · NA · not yet recruiting
- NCT07506135 — Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars. · NA · completed
- NCT07179835 — To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05878249 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Postgraduate Institute of Dental Sciences Rohtak
- Last refreshed: 8 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05878249.
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