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NCT05871242
Study to Investigate the Treatment Benefit of Probiotic Lactobacillus Crispatus M247 in Women Undergoing Homologous Level 2 Assisted Reproductive Technology (ART) Procedures
NA trial testing Probiotic Lactobacillus crispatus M247 in Fertility Issues in 160 participants. Completed in 30 June 2022.
31 December 2021
Quick facts
| Lead sponsor | Dr. Amjad Khan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 160 |
| Start date | 10 January 2020 |
| Primary completion | 31 December 2021 |
| Estimated completion | 30 June 2022 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Probiotic Lactobacillus crispatus M247
Conditions studied
- Fertility Issues — all drugs for Fertility Issues →
Sponsor
Dr. Amjad Khan
Who can join
Adults 18 to 45, female only, with Fertility Issues. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present study is aimed to explore the treatment effect from the intake of probiotic Lactobacillus crispatus M247 in the improvement of clinical and psychological aspects in women undergoing homologous level 2 ART procedures.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
All Properties of Infertility Microbiome in a Review Article.
Elahi Z, Mokhtaryan M, Mahmoodi S, Shahroodian S, et al · · 2025 · cited 3× · PMID 40059472 · DOI 10.1002/jcla.25158 -
Effect of L. crispatus M247 Administration on Pregnancy Outcomes in Women Undergoing IVF: A Controlled, Retrospective, Observational, and Open-Label Study
Di Pierro F, Sinatra F, Cester M, Da Ros L, et al · · 2023
Verify or expand the search:
- PubMed search for NCT05871242
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Dr. Amjad Khan trials
Trials by the same sponsor.
- NCT06852274 — Clostridium Butyricum CBM588® vs. Rifaximin for Symptomatic Uncomplicated Diverticular Disease (SUDD): A Real-World Retr · NA · completed
- NCT05871255 — Natural Topical Treatment for Vulvar and Vaginal Atrophy · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05871242 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Amjad Khan
- Last refreshed: 13 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05871242.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing