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NCT07050537
A Multicenter Prospective Randomized Controlled Clinical Trial Comparing Constant (5%) Versus Sequential (5%-2%) Oxygen Concentration Embryo Culture Protocols in Assisted Reproductive Technology
NA trial testing Constant oxygen concentration protocols in embryo culture in Fertility Issues in 980 participants. Currently enrolling.
31 March 2027
Quick facts
| Lead sponsor | The First Affiliated Hospital with Nanjing Medical University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 980 |
| Start date | 1 March 2025 |
| Primary completion | 31 March 2027 |
| Estimated completion | 31 August 2027 |
| Sites | 5 locations across China |
Drugs / interventions tested
- Constant oxygen concentration protocols in embryo culture
- Sequential oxygen concentration protocols in embryo culture
Conditions studied
- Fertility Issues — all drugs for Fertility Issues →
- Blastocyst IVF — all drugs for Blastocyst IVF →
- Embryo Culture — all drugs for Embryo Culture →
Sponsor
The First Affiliated Hospital with Nanjing Medical University
Who can join
Adults 20 to 40, female only, with Fertility Issues or Blastocyst IVF. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate whether there were significant differences in the effects of constant (5%) versus sequential (5%-2%) oxygen concentration protocols in embryo culture on term live birth rates. This study will be conducted in five centers including the Clinical Center of Reproductive Medicine, First Affiliated Hospital of Nanjing Medical Universit. 980 women who wish to undergo blastocyst transplantation will be included in the study. The study data will be analyzed statistically.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07050537
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07050537 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The First Affiliated Hospital with Nanjing Medical University
- Last refreshed: 3 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07050537.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing