Last reviewed · How we verify
NCT05858346
Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder
NA trial testing Transdiagnostic Behavior Therapy in Social Anxiety Disorder in 264 participants. Currently enrolling.
1 April 2027
Quick facts
| Lead sponsor | VA Office of Research and Development |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 264 |
| Start date | 1 April 2024 |
| Primary completion | 1 April 2027 |
| Estimated completion | 31 October 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Transdiagnostic Behavior Therapy
- Cognitive Behavioral Therapy for Social Anxiety Disorder
Conditions studied
- Social Anxiety Disorder — all drugs for Social Anxiety Disorder →
Sponsor
VA Office of Research and Development — full company profile →
Who can join
Adults 18 to 80, any sex, with Social Anxiety Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective treatment for individuals with depressive/anxiety disorders. However, CBT is largely underutilized within the Department of Veterans Affairs due to the cost and burden of trainings necessary to deliver all of the related disorder-specific treatments (DSTs). Transdiagnostic Behavior Therapy (TBT), in contrast, is specifically designed to address numerous distinct disorders within a single protocol in Veterans with depressive/anxiety disorders. The proposed research seeks to evaluate the efficacy of TBT by assessing psychiatric symptomatology and related impairment outcomes in Veterans with social anxiety disorder and comorbid posttraumatic stress via a randomized controlled trial of TBT and an existing DST. Assessments will be completed at pre-, mid-, and post-treatment, and at 6-month follow-up. Process variables also will be investigated.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05858346
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transdiagnostic Behavior Therapy
Trials testing the same drug.
- NCT04293341 — Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder · NA · completed
- NCT01947647 — Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders · NA · completed
Other recruiting trials for Social Anxiety Disorder
Currently open trials in the same condition.
- NCT06661460 — Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders · NA · recruiting
- NCT06934525 — Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings · NA · recruiting
- NCT06274112 — Using TMS to Understand Neural Processes of Social Motivation · NA · recruiting
- NCT06942429 — Stepped Versus Stratified Care for Anxiety Disorders in Youth · NA · recruiting
- NCT06514495 — Differential Effects of in Vivo and Virtual Exposure Therapy in Agoraphobia · NA · recruiting
Other VA Office of Research and Development trials
Trials by the same sponsor.
- NCT07456150 — Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care · Phase 1 · not yet recruiting
- NCT06746727 — The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veteran · NA · not yet recruiting
- NCT07362576 — Perinatal Peer Support for Veterans With Serious Mental Illness · NA · not yet recruiting
- NCT06766331 — Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans · NA · not yet recruiting
- NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05858346 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
- Last refreshed: 10 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05858346.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing