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NCT05853484: FIT4Cirrhotics
Home-based Bimodal Lifestyle Intervention in Patients With Liver Cirrhosis Awaiting Orthotopic Liver Transplantation
NA trial testing Bimodal lifestyle program in Liver Cirrhosis in 16 participants. Not yet recruiting.
1 April 2025
Quick facts
| Lead sponsor | University Medical Center Groningen |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 16 |
| Start date | 1 September 2024 |
| Primary completion | 1 April 2025 |
| Estimated completion | 1 August 2025 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Bimodal lifestyle program
Conditions studied
- Liver Cirrhosis — all drugs for Liver Cirrhosis →
- Liver Transplant; Complications — all drugs for Liver Transplant; Complications →
- Physical Inactivity — all drugs for Physical Inactivity →
Sponsor
University Medical Center Groningen
Who can join
18 and older, any sex, with Liver Cirrhosis or Liver Transplant; Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Chronic liver disease eventually results in liver cirrhosis and is associated with an increasing deterioration in patients' physical fitness. As there is currently limited evidence regarding the effects of a home-based exercise program in patients with liver cirrhosis awaiting OLT, and physical frailty rates are particularly high in this patient population, this group has the investigators specific interest. The primary aim of this study is to assess the effect of a semi-supervised home-based bimodal lifestyle program, consisting of interval and endurance training and peripheral resistance training on aerobic capacity in patients with liver cirrhosis awaiting OLT
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
'Effects of a home-based bimodal lifestyle intervention in frail patients with end-stage liver disease awaiting orthotopic liver transplantation': study protocol of a non-randomised clinical trial.
Wijma AG, Bongers BC, Annema C, Dekker R, et al · · 2024 · cited 2× · PMID 38286689 · DOI 10.1136/bmjopen-2023-080430
Verify or expand the search:
- PubMed search for NCT05853484
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Liver Cirrhosis
Currently open trials in the same condition.
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Other University Medical Center Groningen trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05853484 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Medical Center Groningen
- Last refreshed: 16 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05853484.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing