NCT05821075 is a Phase 1/Phase 2 clinical trial of Prednisolone in Bell Palsy, sponsored by October 6 University.

Who is sponsoring NCT05821075?

NCT05821075 is sponsored by October 6 University.

What drugs are being tested in NCT05821075?

Interventions in NCT05821075: Prednisolone, Cerebrolysin.

What condition does NCT05821075 study?

NCT05821075 studies Bell Palsy.

Is NCT05821075 still recruiting?

NCT05821075 is currently recruiting now. Last updated 28 July 2025.

Last reviewed 2025-07-28 · How we verify

NCT05821075

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy

Recruiting now Phase 1/Phase 2 Last updated 28 July 2025

What this trial tests

Phase 1/Phase 2 trial testing Prednisolone in Bell Palsy in 90 participants. Currently enrolling.

Timeline

24 August 2023

Primary endpoint
1 January 2026

1 February 2026

Quick facts

Lead sponsor	October 6 University
Phase	Phase 1/Phase 2
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	90
Start date	24 August 2023
Primary completion	1 January 2026
Estimated completion	1 February 2026
Sites	1 location across Egypt

Drugs / interventions tested

Prednisolone — full drug profile →
Cerebrolysin — full drug profile →

Conditions studied

Bell Palsy — all drugs for Bell Palsy →

Sponsor

October 6 University

Who can join

Adults 18 to 60, any sex, with Bell Palsy. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

change in scores of the house Brackman grading system HB
Time frame: at baseline, after 1 week, after 3 week
changes in scores of the Sunnybrook grading system.
Time frame: at baseline, after 1 week, after 3 week

Sponsor's own description

Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies. Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Prednisolone

Trials testing the same drug.

NCT07072585 — Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leuk · Phase 2, PHASE3 · not yet recruiting
NCT07210008 — "Randomized Controlled Trial Testing the Efficacy of Corticosteroid Therapy Versus Placebo in Fibrotic Hypersensitivity · Phase 3 · not yet recruiting
NCT06953791 — Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Pat · Phase 2 · recruiting
NCT07052929 — Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators · Phase 1, PHASE2 · recruiting
NCT07252271 — Very Low Dose Prednisolone on Newly Diagnosed Rheumatoid Arthritis · Phase 4 · not yet recruiting

Other recruiting trials for Bell Palsy

Currently open trials in the same condition.

NCT07519421 — Different Laser Frequencies on Neuropathic Outcomes in Patients With Bell's Palsy · NA · recruiting
NCT06778473 — Intradermal Acupuncture and Self-rehabilitation Program in Patients With Severe Bell's Palsy · NA · recruiting
NCT06732622 — Laser Acupuncture for Idiopathic Bell's Palsy · NA · recruiting
NCT06459830 — Mime Therapy With and Without Neural Mobilization in Bell's Palsy. · NA · recruiting
NCT06742580 — The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients · recruiting

Other October 6 University trials

Trials by the same sponsor.

NCT07235072 — Passive Fit and Time Efficiency in All On-X Implants Protocols Using Photogrammetry, Splinted Scan Bodies, and Conventio · NA · not yet recruiting
NCT07403851 — Effect of Scanning Technology on the Accuracy of Digitally Customized Intraradicular Attachments · NA · not yet recruiting
NCT07305792 — High Tone Power Therapy on Lumbosacral Radiculopathy Patients · NA · completed
NCT07132736 — Impact of Underwater Exercise Versus Regular Aerobic Exercise on Quality of Life and Power of Muscle · NA · recruiting
NCT07350655 — Efficacy of Virtual Reality-based Training in Patients With Chronic Non-specific Low Back Pain · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05821075 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by October 6 University
Last refreshed: 28 July 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05821075.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing