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NCT05820178
tDCS and rTMS in Patients With Early Disorders of Consciousness
NA trial testing tDCS in Disorder of Consciousness in 120 participants. Status unknown.
1 April 2026
Quick facts
| Lead sponsor | Xuanwu Hospital, Beijing |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 1 May 2023 |
| Primary completion | 1 April 2026 |
| Estimated completion | 1 April 2026 |
Drugs / interventions tested
- tDCS — full drug profile →
- rTMS
Conditions studied
- Disorder of Consciousness — all drugs for Disorder of Consciousness →
- Stroke — all drugs for Stroke →
- Ischemic-hypoxic Encephalopathy — all drugs for Ischemic-hypoxic Encephalopathy →
Sponsor
Xuanwu Hospital, Beijing
Who can join
Adults 18 to 80, any sex, with Disorder of Consciousness or Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized controlled study was conducted to explore the efficacy of early transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS) to promote wakefulness in patients with disorder of consciousness (DOC). In order to improve the prognosis of DOC patients with nontraumatic brain injury, we compared the effects of tDCS and rTMS on clinical behavior and neurophysiological performance, and selected a wake-up technique that could improve the prognosis of DOC patients with nontraumatic brain injury as early as possible, so as to reduce the pain of patients and their loved ones, and to reduce the economic burden of society and families.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Advances in Therapies to Treat Neonatal Hypoxic-Ischemic Encephalopathy.
Ranjan AK, Gulati A. · · 2023 · cited 41× · PMID 37892791 · DOI 10.3390/jcm12206653
Verify or expand the search:
- PubMed search for NCT05820178
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of tDCS
Trials testing the same drug.
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- NCT07331779 — Effect of tDCS Timing on Motor Recovery in Acute Stroke Rehabilitation · NA · not yet recruiting
- NCT06972368 — Home-Based tDCS for Depression in BPD · NA · recruiting
Other recruiting trials for Disorder of Consciousness
Currently open trials in the same condition.
- NCT06896279 — Study on the Effectiveness and Safety of Temporal Interference Stimulation in Treating Patients With Severe Consciousnes · NA · recruiting
- NCT06515132 — Efficacy and Safety of Spinal Cord Stimulation in Patients With Spinal Cord Stimulation · NA · recruiting
- NCT06469983 — Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial · NA · recruiting
- NCT06527573 — Effects of rTMS With Different Stimulation Spots in Patients With Disorders of Consciousness · NA · recruiting
- NCT06635291 — Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE) · recruiting
Other Xuanwu Hospital, Beijing trials
Trials by the same sponsor.
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- NCT07457125 — The Effect of CB-Exo-A600 in Mild to Moderate Alzheimer's Disease · Phase 1, PHASE2 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05820178 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xuanwu Hospital, Beijing
- Last refreshed: 26 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05820178.
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