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NCT05809089
HFNO in Pneumonia Patients Presenting With Acute Hypoxemic Respiratory Failure
NA trial testing High flow nasal cannula (HFNC) in Pneumonia in 200 participants. Completed in 20 February 2023.
20 January 2023
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | supportive care |
| Enrollment | 200 |
| Start date | 20 November 2020 |
| Primary completion | 20 January 2023 |
| Estimated completion | 20 February 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- High flow nasal cannula (HFNC)
- Noninvasive ventilation (NIV)
Conditions studied
- Pneumonia — all drugs for Pneumonia →
Sponsor
Assiut University
Who can join
Adults 18 to 70, any sex, with Pneumonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
High-flow nasal oxygen (HFNO) therapy is an upcoming and beneficial modality for patients with acute hypoxemic respiratory failure (AHRF). To evaluate whether early use of HFNO in pneumonia patients with (AHRF) can reduce the need for invasive ventilation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Outcome of Early Initiation of High-flow Nasal Oxygen Therapy among Pneumonia Patients Presenting with Acute Hypoxemic Respiratory Failure.
Magdy DM. · · 2024 · cited 1× · PMID 39239186 · DOI 10.5005/jp-journals-10071-24769
Verify or expand the search:
- PubMed search for NCT05809089
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High flow nasal cannula (HFNC)
Trials testing the same drug.
- NCT07528404 — High-Flow Nasal Cannula After Major Abdominal Surgery to Prevent Postoperative Pulmonary Complications · NA · not yet recruiting
- NCT05499039 — High Flow Nasal Cannula Versus Non-Invasive (NIV)in Both Hypoxemic and Hypercapnic Respiratory Failure. · NA · unknown
- NCT04715243 — Comparison of High Flow Nasal Cannula (HFNC), Face-mask Non-Invasive Ventilation (NIV) & Helmet NIV in COVID-19 ARDS Pat · NA · terminated
- NCT05075668 — Efficacy of HFNC as an Alternative to CPAP Therapy in Surgical Patients With Suspected Moderate to Severe OSA · NA · completed
- NCT02662387 — External Nasal Dilator and Oxygen Therapy in Respiratory Failure · NA · completed
Other recruiting trials for Pneumonia
Currently open trials in the same condition.
- NCT07453966 — Efficacy and Safety of Intrapulmonary Percussive Ventilation in Patients With Pulmonary Infection Receiving Invasive Mec · NA · recruiting
- NCT07251465 — A Study to Learn How Effective is PCV20 to Help Stop Adults Who Have a Higher Chance of Getting Pneumonia · active not recruiting
- NCT07311343 — Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia · Phase 4 · recruiting
- NCT07298889 — High PEEP in Noninvasive Ventilation Patients With Pneumonia or ARDS · NA · recruiting
- NCT06911658 — Infectious Complications After Esophagectomy · recruiting
Other Assiut University trials
Trials by the same sponsor.
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- NCT07234526 — Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients · not yet recruiting
- NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
- NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
- NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05809089 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 25 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05809089.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing