Last reviewed · How we verify
NCT05790356: FeMiTRA
Fecal Microbial Transplantation for Rheumatoid Arthritis Trial
NA trial testing Fecal Microbial transplant in Arthritis in 30 participants. Currently enrolling.
1 August 2025
Quick facts
| Lead sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 August 2023 |
| Primary completion | 1 August 2025 |
| Estimated completion | 1 April 2026 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Fecal Microbial transplant — full drug profile →
- Placebo capsules — full drug profile →
Conditions studied
- Arthritis — all drugs for Arthritis →
- Arthritis, Rheumatoid — all drugs for Arthritis, Rheumatoid →
- Fecal Microbiota Transplantation — all drugs for Fecal Microbiota Transplantation →
Sponsor
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Who can join
18 and older, any sex, with Arthritis or Arthritis, Rheumatoid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial will investigate the effects of capsules containing stool from healthy donors, called fecal microbial transplant (FMT), in rheumatoid arthritis patients.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Gut Microbiota Modulation: A Novel Strategy for Rheumatoid Arthritis Therapy.
Chasov V, Gilyazova E, Ganeeva I, Zmievskaya E, et al · · 2024 · cited 10× · PMID 39766360 · DOI 10.3390/biom14121653 -
Innovations in immunotherapy for autoimmune diseases: recent breakthroughs and future directions.
Alsayb MA. · · 2025 · cited 2× · PMID 41041324 · DOI 10.3389/fimmu.2025.1647066 -
The Oral-Gut-Immune-Nutrition Axis in Rheumatoid Arthritis: Molecular Mechanisms and Therapeutic Implications.
Reytor-González C, Román-Galeano NM, Aules-Curicama LS, Cevallos-Villacis CD, et al · · 2026 · PMID 41828603 · DOI 10.3390/ijms27052385
Verify or expand the search:
- PubMed search for NCT05790356
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05790356 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Last refreshed: 21 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05790356.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing