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NCT07106931: START

Early STratification of Acute ARThritis

Recruiting now Last updated 6 August 2025
What this trial tests

trial testing This is an observational study with no intervention in Arthritis in 400 participants. Currently enrolling.

Timeline
5 November 2024
Primary endpoint
31 December 2044
31 December 2044

Quick facts

Lead sponsorDiakonhjemmet Hospital
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment400
Start date5 November 2024
Primary completion31 December 2044
Estimated completion31 December 2044
Sites1 location across Norway

Drugs / interventions tested

Conditions studied

Sponsor

Diakonhjemmet Hospital

Who can join

18 and older, any sex, with Arthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The prospective observational study "Early STratification of acute inflammatory ARThritis" (START) aims to build a platform for identification of markers for early stratification of inflammatory arthritis to ensure timely diagnosis and correct initial treatment. Management of early-stage inflammatory arthritis is a daily challenge for the rheumatologist and encompasses a range of conditions. Stratification is needed both for optimal diagnostics and for personalising therapy, but is hampered by a lack of tools. Current evaluation is inadequate for early diagnosis and treatment of inflammatory joint diseases as well as for timely diagnosis of infections. The clinical role of novel biomarkers needs to be investigated in large patient samples. In the START study, an extensive data collection will be performed to build a platform for identification and validation of biomarkers for stratification of early-stage inflammatory arthritis. The study has an ambitious goal of improving patient care by increased understanding of the disease. The project applies a unique multitude of approaches to characterisation of patients, including modern imaging techniques, analyses of synovial fluid and -biopsies, genetic and epigenetic markers, proteomics, microbiota analyses and immunological markers. The results will enable clinicians to make better informed treatment decisions for the individual patient with early-stage inflammatory arthritis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Arthritis

Currently open trials in the same condition.

Other Diakonhjemmet Hospital trials

Trials by the same sponsor.

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Data sources for this page

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