Last reviewed · How we verify
NCT05770856: METADIAG
Clinical Metagenomic of Post-traumatic Infections
trial testing Metagenomic sequencing in Fractures, Bone in 25 participants. Completed in 15 July 2023.
15 July 2023
Quick facts
| Lead sponsor | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 25 |
| Start date | 27 April 2023 |
| Primary completion | 15 July 2023 |
| Estimated completion | 15 July 2023 |
| Sites | 1 location across France |
Drugs / interventions tested
- Metagenomic sequencing
Conditions studied
- Fractures, Bone — all drugs for Fractures, Bone →
- Infections — all drugs for Infections →
Sponsor
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Who can join
18 and older, any sex, with Fractures, Bone or Infections. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Treatment of fracture related infection is challenging and often lead to failure in such situation that carry a high health cost burden. These infections are often polymicrobial, making the identification of all involved microorganisms a major concern to provide tailored antibiotic treatment. Culture-independent methods are needed to better represent the microbial diversity of infected wounds. Metagenomic sequencing might lead to an accurate microbiome characterization in infected trauma-related wound. Preliminary studies have reported results of metagenomic sequencing in diabetic foot infection but data focusing on non-diabetic infected patients are scarce. The impact of post-traumatic infected wound microbiome needs to be assessed, with regards to bacterial abundance, diversity including at the strain level and functional genes, along with their longitudinal evolution and association with clinical outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05770856
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Metagenomic sequencing
Trials testing the same drug.
- NCT07256405 — Metagenomic Next-Generation Sequencing for the Diagnosis of Fracture-related Infection · active not recruiting
Other recruiting trials for Fractures, Bone
Currently open trials in the same condition.
- NCT06812481 — Anticholinergic Burden and Osteoporosis in Rheumatoid Arthritis · recruiting
- NCT06754137 — Assessing AI-Supported Fracture Detection in Emergency Care Units · NA · recruiting
- NCT06113211 — Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures · Phase 4 · recruiting
- NCT06013852 — Boneview-ED - Impact of Artificial Intelligence Detecting Fractures in the Emergence Department : a Pragmatic Prospectiv · NA · recruiting
- NCT06256458 — Prospective Registry to Evaluate Outcomes of NanoBone® Bone Graft in Acute Trauma · recruiting
Other Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer trials
Trials by the same sponsor.
- NCT07355582 — Injury Incidence, Severity and Burden in Elite Youth Rugby Players · recruiting
- NCT06865053 — Screening for Heart Failure in General Medicine Consultations · completed
- NCT06863246 — Postural Control in Chronic Obstructive Pulmonary Disease · completed
- NCT06871670 — Force Control in Chronic Obstructive Pulmonary Disease · completed
- NCT06857396 — Tracheal Exposure Without Tracheostomy Completion in Trans-oral Robotic Oncologic Surgery · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05770856 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
- Last refreshed: 29 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05770856.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing