Last reviewed · How we verify
NCT05746143
The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion
Phase 4 trial testing Zolpidem Tartrate 10 mg in Spine Fusion in 140 participants. Currently enrolling.
31 January 2026
Quick facts
| Lead sponsor | University of Southern California |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | supportive care |
| Enrollment | 140 |
| Start date | 1 February 2022 |
| Primary completion | 31 January 2026 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Zolpidem Tartrate 10 mg
- Placebo
Conditions studied
- Spine Fusion — all drugs for Spine Fusion →
- Lumbar Spine Degeneration — all drugs for Lumbar Spine Degeneration →
- Pain, Postoperative — all drugs for Pain, Postoperative →
- Lumbar Spine Spondylosis — all drugs for Lumbar Spine Spondylosis →
Sponsor
University of Southern California
Who can join
Adults 18 to 75, any sex, with Spine Fusion or Lumbar Spine Degeneration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05746143
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Spine Fusion
Currently open trials in the same condition.
- NCT06975072 — Effect of Magnesium on Neuromonitoring · Phase 4 · recruiting
- NCT04679844 — Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Au · NA · recruiting
- NCT05957822 — Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery · Phase 4 · recruiting
- NCT06140927 — Effect of Ketamine on Intraoperative Motor Evoked Potentials · Phase 3 · recruiting
- NCT05367609 — Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB) · NA · recruiting
Other University of Southern California trials
Trials by the same sponsor.
- NCT07288463 — Hearing Loss and Genetic Risks for Alzheimer's Disease and Related Dementia · NA · not yet recruiting
- NCT05914233 — Non-invasive Ultrasound Retinal Stimulation for Vision Restoration · NA · not yet recruiting
- NCT06163664 — Role of ChatGPT in Vestibular Schwannoma Management · NA · withdrawn
- NCT07332312 — A Culturally Informed Patient Navigation Program (CFPN) to Reduce Delays Between Diagnosis and Treatment in American Ind · NA · not yet recruiting
- NCT07290478 — Encouraging Older Adults and Adults With Serious Illness to Designate a Health Care Proxy · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05746143 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Southern California
- Last refreshed: 25 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05746143.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing