NCT05726695 is a clinical trial of microRNA test in Heart Failure, sponsored by University Hospital Ostrava.

Who is sponsoring NCT05726695?

NCT05726695 is sponsored by University Hospital Ostrava.

What drugs are being tested in NCT05726695?

Interventions in NCT05726695: microRNA test, Heart ultrasound examination.

What condition does NCT05726695 study?

NCT05726695 studies Heart Failure, Heart Dilation, Left Ventricular Hypertrophy.

Is NCT05726695 still recruiting?

NCT05726695 is currently status unknown. Last updated 14 February 2023.

Last reviewed 2023-02-14 · How we verify

NCT05726695

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases

Status unknown Last updated 14 February 2023

What this trial tests

trial testing microRNA test in Heart Failure in 200 participants. Status unknown.

Timeline

1 June 2018

Primary endpoint
31 December 2022

31 December 2023

Quick facts

Lead sponsor	University Hospital Ostrava
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	200
Start date	1 June 2018
Primary completion	31 December 2022
Estimated completion	31 December 2023
Sites	1 location across Czechia

Drugs / interventions tested

microRNA test
Heart ultrasound examination

Conditions studied

Heart Failure — all drugs for Heart Failure →
Heart Dilation — all drugs for Heart Dilation →
Left Ventricular Hypertrophy — all drugs for Left Ventricular Hypertrophy →

Sponsor

University Hospital Ostrava

Who can join

Adults 18 to 99, any sex, with Heart Failure or Heart Dilation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to determine the analytical characteristics of the microRNA enzymatic immunoassay (miREIA) method and to determine various relations among miRNA biomarkers and heart failure (HF) with reduced ejection fraction(HFrEF). The investigators assume that there are correlations between levels of selected miRNA and HFrEF. These correlations provide information to formulate pathophysiological conclusions, which will significantly contribute to early diagnostics and also the treatment of this disease.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Extracellular Vesicles in Diabetic Cardiomyopathy-State of the Art and Future Perspectives.
Zygmunciak P, Stróżna K, Błażowska O, Mrozikiewicz-Rakowska B. · · 2024 · cited 5× · PMID 38892303 · DOI 10.3390/ijms25116117
Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics.
Wang Y, Yuan Y, Tang J. · · 2025 · cited 1× · PMID 40457135 · DOI 10.1007/s12265-025-10629-8

Verify or expand the search:

Other recruiting trials for Heart Failure

Currently open trials in the same condition.

NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting

Other University Hospital Ostrava trials

Trials by the same sponsor.

NCT07177183 — Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure · NA · recruiting
NCT07374289 — On Scene ECPR in Ostrava · NA · recruiting
NCT07041086 — Prehospital ECPR in Moravia Silesia Region · recruiting
NCT07009652 — Optimization of Transport and Use of a Mobile ECMO Team in Patients With Sudden Cardiac Arrest in the Moravian-Silesian · recruiting
NCT06921746 — Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05726695 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital Ostrava
Last refreshed: 14 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05726695.

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