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NCT05709873
Narcolepsy Nightmare Study
NA trial testing Imagery rehearsal therapy in Narcolepsy in 7 participants. Completed in 30 April 2024.
30 April 2024
Quick facts
| Lead sponsor | Northwestern University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 7 |
| Start date | 22 February 2023 |
| Primary completion | 30 April 2024 |
| Estimated completion | 30 April 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Imagery rehearsal therapy
- Targeted dream control
Conditions studied
- Narcolepsy — all drugs for Narcolepsy →
- Narcolepsy Type 1 — all drugs for Narcolepsy Type 1 →
- Narcolepsy With Cataplexy — all drugs for Narcolepsy With Cataplexy →
- Narcolepsy Type 2 — all drugs for Narcolepsy Type 2 →
Sponsor
Northwestern University
Who can join
18 and older, any sex, with Narcolepsy or Narcolepsy Type 1. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to test two behavioral treatments for nightmares in adults with narcolepsy. The main questions it aims to answer are: * Is imagery rehearsal therapy (IRT) effective for narcolepsy-related nightmares? * Does adding targeted dream control (TDC) to IRT make it more effective? Participants will be randomized to one of two treatment groups and will be asked to: * Complete a daily log of sleep symptoms for up to 13 weeks. * Attend 7 sessions of treatment. * Complete questionnaires before and after treatment. * Go to the research lab in Evanston, IL to complete a sleep study during a daytime nap (Chicago area residents only).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Treating narcolepsy-related nightmares with cognitive behavioural therapy and targeted lucidity reactivation: A pilot study.
Mundt JM, Pruiksma KE, Konkoly KR, Casiello-Robbins C, et al · · 2025 · cited 4× · PMID 39438131 · DOI 10.1111/jsr.14384
Verify or expand the search:
- PubMed search for NCT05709873
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05709873 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Northwestern University
- Last refreshed: 12 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05709873.
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