Last reviewed · How we verify
Narcolepsy
Approved treatments
- Xelstrym · UCB
Xelstrym works by blocking the reuptake of noradrenaline, allowing it to stay in the brain for longer and increasing alertness and focus. - Xyrem · Jazz Pharmaceuticals
- Amphetamine Sulfate · UCB
- Wakix · Harmony
Wakix works by blocking histamine H3 receptors in the brain, allowing more histamine to be available to regulate sleep-wake cycles. - Amphetamine Sulfate · Azurity
- Nuvigil · Nuvo Pharms
Nuvigil works by selectively targeting the D(2) dopamine receptor to increase wakefulness and alertness. - Ritalin · Novartis
- Concerta · Lei Lei, MD
- Aponeuron
Aponeuron works by increasing the levels of certain neurotransmitters in the brain, such as dopamine and norepinephrine, to enhance alertness and wakefulness. - DEXTROAMPHETAMINE
- Provigil · Nuvo Pharms
Provigil works by increasing the activity of certain neurotransmitters in the brain, such as dopamine, to help regulate sleep-wake cycles.
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Narcolepsy patent landscape — cliff calendar, originator estates, attackable patents
- Narcolepsy treatment landscape brief
- Narcolepsy treatment updates RSS
Frequently asked questions about Narcolepsy
What drugs treat Narcolepsy?
Tracked treatments include Xelstrym, Xyrem, Amphetamine Sulfate, Wakix, Nuvigil, Ritalin, Concerta, Aponeuron.
What is the treatment for Narcolepsy?
Standard treatment for Narcolepsy includes Xelstrym, Xyrem, Amphetamine Sulfate, Wakix, Nuvigil. See the treatment landscape page for first-line, second-line and salvage options.
Related
- Treatment landscape: Narcolepsy patent cliff · Narcolepsy CI report
- Treatment: Xelstrym · UCB
- Treatment: Xyrem · Jazz Pharmaceuticals
- Treatment: Amphetamine Sulfate · UCB
- Treatment: Wakix · Harmony
- Treatment: Amphetamine Sulfate · Azurity
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing