NCT05709782 is a Phase 2 clinical trial of Spine Radiosurgery in Spinal Disease, sponsored by M.D. Anderson Cancer Center.

Who is sponsoring NCT05709782?

NCT05709782 is sponsored by M.D. Anderson Cancer Center.

What drugs are being tested in NCT05709782?

Interventions in NCT05709782: Spine Radiosurgery, Magnetic Resonance imaging, MR-LINAC.

What condition does NCT05709782 study?

NCT05709782 studies Spinal Disease.

Is NCT05709782 still recruiting?

NCT05709782 is currently recruiting now. Last updated 14 January 2026.

Last reviewed 2026-01-14 · How we verify

NCT05709782

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Phase II Cohort of Spinal Stereotactic Radiotherapy in Patients Using a MR LINAC

Recruiting now Phase 2 Last updated 14 January 2026

What this trial tests

Phase 2 trial testing Spine Radiosurgery in Spinal Disease in 40 participants. Currently enrolling.

Timeline

9 May 2023

Primary endpoint
31 January 2026

31 January 2026

Quick facts

Lead sponsor	M.D. Anderson Cancer Center
Phase	Phase 2
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	40
Start date	9 May 2023
Primary completion	31 January 2026
Estimated completion	31 January 2026
Sites	1 location across United States

Drugs / interventions tested

Spine Radiosurgery
Magnetic Resonance imaging
MR-LINAC

Conditions studied

Spinal Disease — all drugs for Spinal Disease →

Sponsor

M.D. Anderson Cancer Center — full company profile →

Who can join

18 and older, any sex, with Spinal Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To learn whether giving spinal stereotactic radiosurgery (SRSS) that uses a more advanced imaging scan method called Magnetic Resonance imaging with a Linear Accelerator (MR-LINAC) during treatment will lead to improved responses to treatment and better quality of life. SRSS is radiation therapy given to the area around your spine.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Treatment of Central Nervous System Tumors on Combination MR-Linear Accelerators: Review of Current Practice and Future Directions.
Bryant JM, Doniparthi A, Weygand J, Cruz-Chamorro R, et al · · 2023 · cited 6× · PMID 37958374 · DOI 10.3390/cancers15215200

Verify or expand the search:

Other trials of Spine Radiosurgery

Trials testing the same drug.

NCT03028337 — Single Versus Multifraction Salvage Spine Stereotactic Radiosurgery for Previously Irradiated Spinal Metastases · Phase 2 · active not recruiting

Other recruiting trials for Spinal Disease

Currently open trials in the same condition.

NCT06407167 — Neuropathic Pain in Patients With Degenerative Lumbar Stenosis · active not recruiting
NCT05610098 — Gene Expression Profiles in Spinal Tuberculosis. · recruiting
NCT04775537 — OssiMend BA in Posterolateral Instrumented Lumbar Fusion · recruiting

Other M.D. Anderson Cancer Center trials

Trials by the same sponsor.

NCT07053020 — A Phase 1b/2 Open-label, Dose-ranging Safety and Efficacy Study of Oral Cladribine in Patients With Acute Myeloid Leukem · Phase 1, PHASE2 · not yet recruiting
NCT07052994 — A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin (GO) in Frontline and · Phase 1 · not yet recruiting
NCT07137481 — Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Che · Phase 2 · not yet recruiting
NCT07162480 — Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Ca · Phase 2 · not yet recruiting
NCT07076498 — Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standar · Phase 1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05709782 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by M.D. Anderson Cancer Center
Last refreshed: 14 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05709782.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing