NCT05700214

Lidocaine Versus ESP - After Bariatric Surgery

Completed NA Last updated 9 April 2025

What this trial tests

NA trial testing Ropivacaine injection in Anesthetics in 279 participants. Completed in 31 December 2023.

Timeline

1 February 2023

Primary endpoint
31 December 2023

31 December 2023

Quick facts

Lead sponsor	Jagiellonian University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	279
Start date	1 February 2023
Primary completion	31 December 2023
Estimated completion	31 December 2023
Sites	1 location across Poland

Drugs / interventions tested

• Ropivacaine injection — full drug profile →
• Lidocaine IV — full drug profile →

Conditions studied

• Anesthetics — all drugs for Anesthetics →
• Local Anesthetics — all drugs for Local Anesthetics →

Sponsor

Jagiellonian University

Who can join

Adults 18 to 70, any sex, with Anesthetics or Local Anesthetics. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The Erector Spinal Block (ESP) is based on the deposition of the local anesthetic in the inter-fascial space between the dorsal extensor muscle and the intercostal muscles at the height of the transverse processes. The scope of the blockade covers the dorsal and ventral branches of the thoracic spinal nerves, but also in most cases the investigetors are able to obtain a wide distribution of the drug into the paravertebral space by "permeating" the local anesthetic through the fascial compartments. The clinical effect of the blockade is due to blocking the nerve structures of the paravertebral space (spinal nerve branches and the sympathetic trunk). The scope of the blockade, after its execution at the level of Th5, most often includes the segments from Th1 to L1.

Lidocaine used in intravenous infusion is one of the recommended components of multidirectional analgesia. Its adjuvant properties make it possible to reduce the amount of opioid drugs used, and thus - to reduce the frequency of their side effects.

The aim of the study is to test the effectiveness and safety of the use of lidocaine infusion or Erector Spinal Block in multimodal analgesic management.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Comparison of Erector Spinae Plane Block and Intravenous Lidocaine in Opioid-Free Anesthesia for Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Trial.
   Maciejewski P, Skladzien T, Tabin L, Cicio M, et al · · 2026 · PMID 41831157 · DOI 10.1007/s11695-026-08558-9