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NCT05692752
Expression of microRNA-133a and microRNA-208b in Acute Myocardial Infarction
trial testing No intervention in Myocardial Infarction, Acute in 10 participants. Completed in 14 January 2023.
10 January 2023
Quick facts
| Lead sponsor | Islamia University of Bahawalpur |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 10 |
| Start date | 28 December 2022 |
| Primary completion | 10 January 2023 |
| Estimated completion | 14 January 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- No intervention
Conditions studied
- Myocardial Infarction, Acute — all drugs for Myocardial Infarction, Acute →
Sponsor
Islamia University of Bahawalpur
Who can join
Adults 35 to 65, any sex, with Myocardial Infarction, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cardiac-enriched micro-RNAs (miRNAs), micro RNA 208b and 133a(MiR-208b, MiR-133a)) corresponds to the health and disorders of the cardiovascular system. An intron of the cardiac myosin heavy chain gene MYH7 encodes miR-208b. It is found on chromosome 14 in humans. Identify new diagnostic biomarkers based on miRNAs, researchers examine the expression of miR-133a and 208b at various time points (04 hours, 08 hours, 12 hours, 24 hours, 48 hours) following the development of the infarct and compared it to the traditional myocardial infarction biomarkers cardiac troponine (cTnl) and Creatine kinase-MB (CK-MB).
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Oxidative Stress and MicroRNAs in Endothelial Cells under Metabolic Disorders.
Minjares M, Wu W, Wang JM. · · 2023 · cited 30× · PMID 37174741 · DOI 10.3390/cells12091341 -
Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics.
Wang Y, Yuan Y, Tang J. · · 2025 · cited 1× · PMID 40457135 · DOI 10.1007/s12265-025-10629-8 -
Expression of microRNA-133a and microRNA-208b in acute myocardial infarction; A randomized clinical trial
Ibrahim S, Osama D, Hegazy A, Hashmi H, et al · · 2023 · DOI 10.21203/rs.3.rs-2995851/v1
Verify or expand the search:
- PubMed search for NCT05692752
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05692752 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Islamia University of Bahawalpur
- Last refreshed: 20 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05692752.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing