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NCT05692752

Expression of microRNA-133a and microRNA-208b in Acute Myocardial Infarction

Completed Last updated 20 January 2023
What this trial tests

trial testing No intervention in Myocardial Infarction, Acute in 10 participants. Completed in 14 January 2023.

Timeline
28 December 2022
Primary endpoint
10 January 2023
14 January 2023

Quick facts

Lead sponsorIslamia University of Bahawalpur
StatusCompleted
Study typeOBSERVATIONAL
Enrollment10
Start date28 December 2022
Primary completion10 January 2023
Estimated completion14 January 2023
Sites1 location across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Islamia University of Bahawalpur

Who can join

Adults 35 to 65, any sex, with Myocardial Infarction, Acute. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiac-enriched micro-RNAs (miRNAs), micro RNA 208b and 133a(MiR-208b, MiR-133a)) corresponds to the health and disorders of the cardiovascular system. An intron of the cardiac myosin heavy chain gene MYH7 encodes miR-208b. It is found on chromosome 14 in humans. Identify new diagnostic biomarkers based on miRNAs, researchers examine the expression of miR-133a and 208b at various time points (04 hours, 08 hours, 12 hours, 24 hours, 48 hours) following the development of the infarct and compared it to the traditional myocardial infarction biomarkers cardiac troponine (cTnl) and Creatine kinase-MB (CK-MB).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Oxidative Stress and MicroRNAs in Endothelial Cells under Metabolic Disorders.
    Minjares M, Wu W, Wang JM. · · 2023 · cited 30× · PMID 37174741 · DOI 10.3390/cells12091341
  2. Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics.
    Wang Y, Yuan Y, Tang J. · · 2025 · cited 1× · PMID 40457135 · DOI 10.1007/s12265-025-10629-8
  3. Expression of microRNA-133a and microRNA-208b in acute myocardial infarction; A randomized clinical trial
    Ibrahim S, Osama D, Hegazy A, Hashmi H, et al · · 2023 · DOI 10.21203/rs.3.rs-2995851/v1

Verify or expand the search:

Other trials of No intervention

Trials testing the same drug.

Other recruiting trials for Myocardial Infarction, Acute

Currently open trials in the same condition.

Other Islamia University of Bahawalpur trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05692752.

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