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NCT05691764
Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
NA trial testing Cyclosporin in Myocardial Injury in 40 participants. Completed in 1 September 2022.
1 December 2021
Quick facts
| Lead sponsor | Indonesia University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 September 2020 |
| Primary completion | 1 December 2021 |
| Estimated completion | 1 September 2022 |
| Sites | 1 location across Indonesia |
Drugs / interventions tested
- Cyclosporin — full drug profile →
- remote ischemic preconditioning
- Placebo
Conditions studied
- Myocardial Injury — all drugs for Myocardial Injury →
- Cardiac Surgery — all drugs for Cardiac Surgery →
Sponsor
Indonesia University
Who can join
Adults 1 to 6, any sex, with Myocardial Injury or Cardiac Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aimed to evaluate the combined effects of cyclosporine and remote ischemic preconditioning on MDA, calcium cytosol concentration, and mitochondrial edema in tetralogy Fallot patients undergoing corrective surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The molecular mechanisms of cardiac development and related diseases.
Li Y, Du J, Deng S, Liu B, et al · · 2024 · cited 53× · PMID 39715759 · DOI 10.1038/s41392-024-02069-8
Verify or expand the search:
- PubMed search for NCT05691764
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05691764 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Indonesia University
- Last refreshed: 20 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05691764.
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