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NCT05691764

Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery

Completed NA Last updated 20 January 2023
What this trial tests

NA trial testing Cyclosporin in Myocardial Injury in 40 participants. Completed in 1 September 2022.

Timeline
1 September 2020
Primary endpoint
1 December 2021
1 September 2022

Quick facts

Lead sponsorIndonesia University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposetreatment
Enrollment40
Start date1 September 2020
Primary completion1 December 2021
Estimated completion1 September 2022
Sites1 location across Indonesia

Drugs / interventions tested

Conditions studied

Sponsor

Indonesia University

Who can join

Adults 1 to 6, any sex, with Myocardial Injury or Cardiac Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study aimed to evaluate the combined effects of cyclosporine and remote ischemic preconditioning on MDA, calcium cytosol concentration, and mitochondrial edema in tetralogy Fallot patients undergoing corrective surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The molecular mechanisms of cardiac development and related diseases.
    Li Y, Du J, Deng S, Liu B, et al · · 2024 · cited 53× · PMID 39715759 · DOI 10.1038/s41392-024-02069-8

Verify or expand the search:

Other trials of Cyclosporin

Trials testing the same drug.

Other recruiting trials for Myocardial Injury

Currently open trials in the same condition.

Other Indonesia University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05691764.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing