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NCT05688592: PETIFI
Usefulness of PET-CT for Invasive Fungal Infection
trial testing PET-CT in Invasive Fungal Infections in 224 participants. Currently enrolling.
31 October 2024
Quick facts
| Lead sponsor | Puerta de Hierro University Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 224 |
| Start date | 27 April 2023 |
| Primary completion | 31 October 2024 |
| Estimated completion | 1 December 2024 |
| Sites | 14 locations across Spain |
Drugs / interventions tested
- PET-CT
Conditions studied
- Invasive Fungal Infections — all drugs for Invasive Fungal Infections →
Sponsor
Puerta de Hierro University Hospital
Who can join
18 and older, any sex, with Invasive Fungal Infections. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this national multicenter prospective cohort study is to learn about the added value of 18F-FDG (18F-2-fluoro-2-deoxy-D-glucose) PET-CT in invasive fungal disease management. The main questions it aims to answer are: 1. Does the use of 18F-FDG PET-CT allow a better characterization of invasive fungal infection (IFI) (performance) compared to the exclusive use of conventional radiological studies in terms of extension/staging and monitoring of response/follow-up ? 2. Does the systematic and protocolized use of 18F-FDG PET-CT in IFI allow a better management of patients with IFI and increase the prognostic value of the initial evaluation? Participants will undergo systematically a 18F-FDG PET-CT as part of the work-up of their invasive fungal disease. Researchers will compare the performance of 18F-FDG PET-CT with standard management without 18F-FDG PET-CT to see if adds value (diagnostic, prognostic, and changes in management).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Determining the usefulness of systematic <sup>18</sup>F-FDG PET/CT for the management of invasive fungal infection (PETIFI project): a prospective national multicentre cohort study protocol.
Gutiérrez A, Rodriguez B, Velasquez K, Gutiérrez I, et al · · 2023 · cited 9× · PMID 37355275 · DOI 10.1136/bmjopen-2023-074240 -
Is neutropenia still the main risk factor for invasive aspergillosis? A contemporary university hospital retrospective cohort of invasive aspergillosis in neutropenic and non-neutropenic patients.
Gutiérrez-Villanueva A, Diego-Yagüe I, Gutiérrez-Martín I, García-Prieto S, et al · · 2025 · cited 4× · PMID 40281569 · DOI 10.1186/s12941-025-00794-8
Verify or expand the search:
- PubMed search for NCT05688592
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Puerta de Hierro University Hospital trials
Trials by the same sponsor.
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- NCT07008729 — Heart Failure Patient Management and Interventions Using Continuous Patient Monitoring Outside Hospitals and Real-world · NA · active not recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05688592 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Puerta de Hierro University Hospital
- Last refreshed: 6 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05688592.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing