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NCT05674760: ReAcTCO2
ReAcT CO2: A Study to Assess TcCO2 to Guide Acute NIV
NA trial testing Trancutaneous CO2 monitoring (using TCM5 device) in Acute Hypercapnic Respiratory Failure in 60 participants. Status unknown.
7 February 2024
Quick facts
| Lead sponsor | Nottingham University Hospitals NHS Trust |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 60 |
| Start date | 10 February 2023 |
| Primary completion | 7 February 2024 |
| Estimated completion | 10 February 2024 |
Drugs / interventions tested
- Trancutaneous CO2 monitoring (using TCM5 device)
- Arterial Blood Gas (ABG) sampling
Conditions studied
- Acute Hypercapnic Respiratory Failure — all drugs for Acute Hypercapnic Respiratory Failure →
Sponsor
Nottingham University Hospitals NHS Trust
Who can join
18 and older, any sex, with Acute Hypercapnic Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Arterial blood sampling is needed to monitor carbon dioxide and PH but is often painful. The aim of this study is to determine whether continuous carbon dioxide monitoring with a skin probe reduces the need for arterial blood sampling by at least 30%. The investigators will also study the safety and effectiveness of skin probe monitoring to manage non-invasive ventilation (NIV).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05674760
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Nottingham University Hospitals NHS Trust trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05674760 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nottingham University Hospitals NHS Trust
- Last refreshed: 6 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05674760.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing