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NCT05668559
Transcranial Magnetic Stimulation and Perioperative Neurocognitive Disorders
NA trial testing repetitive transcranial magnetic stimulation in Postoperative Cognitive Dysfunction in 280 participants. Status unknown.
1 March 2026
Quick facts
| Lead sponsor | Anshi Wu |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 280 |
| Start date | 1 October 2023 |
| Primary completion | 1 March 2026 |
| Estimated completion | 1 April 2026 |
Drugs / interventions tested
- repetitive transcranial magnetic stimulation
- Sham Stimulation
Conditions studied
- Postoperative Cognitive Dysfunction — all drugs for Postoperative Cognitive Dysfunction →
- Repetitive Transcranial Magnetic Stimulation — all drugs for Repetitive Transcranial Magnetic Stimulation →
Sponsor
Anshi Wu
Who can join
18 and older, any sex, with Postoperative Cognitive Dysfunction or Repetitive Transcranial Magnetic Stimulation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To investigate the impact of rTMS on the incidence of perioperative neurocognitive disorders in patients after after cardiac surgerysurgery. To explore the underlying mechanisms behind the efficacy.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The effect of repetitive transcranial magnetic stimulation (rTMS) on perioperative neurocognitive disorders in patients after cardiac surgery: study protocol for a randomized controlled trial.
Wang J, Wang X, Li S, Yang J, et al · · 2025 · PMID 40707956 · DOI 10.1186/s13063-025-08988-3 -
The Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on Perioperative Neurocognitive Disorders in Patients after Cardiac Surgery: Study Protocol for a Randomized Controlled Trial
Wang J, Wang X, Li S, Yang J, et al · · 2024 · DOI 10.21203/rs.3.rs-3298051/v1
Verify or expand the search:
- PubMed search for NCT05668559
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT07106398 — The Effectiveness of rTMS on Improving Food Craving and Weight Control in Adults Without Serious Mental Illness · NA · recruiting
- NCT06813313 — Theta Burst Stimulation With an 8-Coil Versus H1-Coil for Resistant Depression · NA · not yet recruiting
- NCT06451809 — Prediction of the Response to a Course of Transcranial Magnetic Stimulation (rTMS) Based on Heart Rate Variability · suspended
Other recruiting trials for Postoperative Cognitive Dysfunction
Currently open trials in the same condition.
- NCT07113483 — Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery · Phase 3 · recruiting
- NCT07452367 — Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery · recruiting
- NCT07000461 — Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass · recruiting
- NCT06689137 — Effects of Dexmedetomidine on Postoperative Neurocognitive Disorder · active not recruiting
- NCT06658769 — Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly · NA · recruiting
Other Anshi Wu trials
Trials by the same sponsor.
- NCT06735183 — Pre-Anesthesia Visit: Analysis of Coverage Rate of Visit Content and Surgical Patients' Understanding of Information · recruiting
- NCT05155969 — Intravenous Esketamine on Prevention of Postoperative Depression in Patients Undergoing Cardiac Surgery · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05668559 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Anshi Wu
- Last refreshed: 5 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05668559.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing