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NCT05653063
ARCHERY - Artificial Intelligence Based Radiotherapy Treatment Planning for Cervical, Head and Neck and Prostate Cancer
trial testing A web-based artificial intelligence (AI) auto-planning tool in Cancer of Prostate in 990 participants. Currently enrolling.
1 December 2025
Quick facts
| Lead sponsor | University College, London |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 990 |
| Start date | 7 December 2023 |
| Primary completion | 1 December 2025 |
| Estimated completion | 1 September 2026 |
| Sites | 6 locations across Jordan, South Africa, Malaysia, India |
Drugs / interventions tested
- A web-based artificial intelligence (AI) auto-planning tool
Conditions studied
- Cancer of Prostate — all drugs for Cancer of Prostate →
- Cancer Head Neck — all drugs for Cancer Head Neck →
- Cancer Cervix — all drugs for Cancer Cervix →
Sponsor
University College, London
Who can join
18 and older, any sex, with Cancer of Prostate or Cancer Head Neck. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to look at whether an Artificial Intelligence (AI) based computer program can automate two components of the radiotherapy treatment pathway to a sufficient quality standard to enable its routine clinical use. The two components include the delineation (outlining) of anatomical areas that are at risk of tumour spread and at risk of radiation damage, and the definition of the position, size and shape of the radiation beams. The AI-based computer programs have been developed to perform tasks that would normally require direct human involvement by oncologists and medical physicists. Proposed advantages include improved treatment accuracy, as well as a reduction in the time (from weeks to minutes) and human resources needed to deliver radiotherapy, which this study will test.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Beyond Standard Radiotherapy: an AI-Driven Framework for Personalized Radiotherapy with a Four-Step Classification in Head and Neck Squamous Cell Carcinoma (HNSCC) Patients.
Guo Y, Aboagye EO, Gujral DM. · · 2025 · PMID 41174258 · DOI 10.1007/s11912-025-01730-x
Verify or expand the search:
- PubMed search for NCT05653063
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University College, London trials
Trials by the same sponsor.
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- NCT07414940 — ACTinium in Castrate-RESistant Prostate Cancer After LUTEtium · Phase 1, PHASE2 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05653063 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University College, London
- Last refreshed: 22 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05653063.
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