NCT05652244 is a NA clinical trial of Mini-implants in Class II Malocclusion, sponsored by Damascus University.

Who is sponsoring NCT05652244?

NCT05652244 is sponsored by Damascus University.

What drugs are being tested in NCT05652244?

Interventions in NCT05652244: Mini-implants, Transpalatal arche (TPA).

What condition does NCT05652244 study?

NCT05652244 studies Class II Malocclusion.

Is NCT05652244 still recruiting?

NCT05652244 is currently completed. Last updated 15 December 2022.

Last reviewed 2022-12-15 · How we verify

NCT05652244

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Levels of Pain, Discomfort, and Functional Impairment With Two Techniques of Retraction

Completed NA Last updated 15 December 2022

What this trial tests

NA trial testing Mini-implants in Class II Malocclusion in 38 participants. Completed in 24 January 2015.

Timeline

13 January 2013

Primary endpoint
3 May 2014

24 January 2015

Quick facts

Lead sponsor	Damascus University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	38
Start date	13 January 2013
Primary completion	3 May 2014
Estimated completion	24 January 2015
Sites	1 location across Syria

Drugs / interventions tested

Mini-implants
Transpalatal arche (TPA)

Conditions studied

Class II Malocclusion — all drugs for Class II Malocclusion →

Sponsor

Damascus University

Who can join

Adults 17 to 27, any sex, with Class II Malocclusion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Thirty-eight patients requiring extraction of maxillary first premolars will participate in the study. They will be divided randomly into two groups: an en-masse retraction group and a two-step group. In each group, anterior teeth retraction will be initiated after completion of the leveling and alignment phase via closed nickel-titanium coil springs applying 150 g of force per side, Mini-implants will be used as an anchor unit in the en-masse retraction group, and TPA in the two-step's retraction group. The levels of pain, discomfort, and functional impairments will be self-reported using a validated questionnaire with a 4-points Likert scale.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Evaluation of the Patient-Reported Outcome Measures (PROMs) With Temporary Skeletal Anchorage Devices in Fixed Orthodontic Treatment: A Systematic Review.
Mousa MM, Hajeer MY, Sultan K, Almahdi WH, et al · · 2023 · cited 15× · PMID 36937120 · DOI 10.7759/cureus.36165
Pain, Discomfort, and Functional Impairments When Retracting Upper Anterior Teeth Using Two-Step Retraction With Transpalatal Arches Versus En-Masse Retraction With Mini-implants: A Randomized Controlled Trial.
Mousa MM, Al-Sibaie S, Hajeer MY. · · 2023 · cited 11× · PMID 36636520 · DOI 10.7759/cureus.33524

Verify or expand the search:

Other recruiting trials for Class II Malocclusion

Currently open trials in the same condition.

NCT05684510 — Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy · NA · recruiting
NCT07340242 — Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II · NA · recruiting
NCT07361172 — Ready-made vs. Custom-made Carriere Motion Appliance · NA · recruiting
NCT06511219 — Maxillary Segmental Distalization Using Digitally Printed Appliances · NA · recruiting
NCT06651944 — Invisalign® System with Mandibular Advancement · NA · recruiting

Other Damascus University trials

Trials by the same sponsor.

NCT07532161 — Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery · NA · not yet recruiting
NCT07515612 — The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic. · NA · recruiting
NCT07272798 — Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension · recruiting
NCT07426523 — Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia. · NA · completed
NCT07366788 — Clinical Outcomes of Mandibular Primary Molar Extraction Using Physics Forceps in Children · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05652244 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Damascus University
Last refreshed: 15 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05652244.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing