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NCT05646160: MTRPs
Effects of MTRPs Therapy in Migraine.
NA trial testing Ischemic Compression of Myofascial Trigger Points (IC-MTRPs) in Migraine in 100 participants. Status unknown.
1 March 2023
Quick facts
| Lead sponsor | Józef Piłsudski University of Physical Education |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 15 January 2018 |
| Primary completion | 1 March 2023 |
| Estimated completion | 2 March 2023 |
| Sites | 1 location across Poland |
Drugs / interventions tested
- Ischemic Compression of Myofascial Trigger Points (IC-MTRPs)
Conditions studied
- Migraine — all drugs for Migraine →
- Pain, Shoulder — all drugs for Pain, Shoulder →
- Trapezius Muscle Strain Left — all drugs for Trapezius Muscle Strain Left →
- Trapezius Muscle Strain Right — all drugs for Trapezius Muscle Strain Right →
Sponsor
Józef Piłsudski University of Physical Education
Who can join
Adults 18 to 65, female only, with Migraine or Pain, Shoulder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Case series, repeated-measures design, pilot study. Adult, female, migraine patients underwent seven Ischemic Compression Myofascial Trigger Points (IC-MTrPs) therapy sessions. The aim of the study is to investigate whether therapy of the shoulder girdle and neck muscles by deactivating MTrPs causes modification of biomechanical and biochemical variables in the blood and reduces headache in people with migraine, improving their quality of life by improving their health. People qualified for the study were divided into 3 groups according to the type of migraine: 1. CM group - patients with chronic migraine 2. EMa group - patients with paroxysmal migraine with aura 3. EMb group - patients with paroxysmal migraine without an aura. All patients underwent 7 interventions in the area of the muscles of the shoulder girdle and neck (by deactivating trigger points) performed every 2 or 3 days. They did not take any headache medications during the treatment period. However, during a migraine attack, they could undergo treatments and research measurements. Biomechanical measurements of the cervical spine, shoulder girdle muscles and blood chemistry were performed before, during and after the patients' therapy. All treatments were performed on the following muscles: * m. trapesius pars descendent (trapezius upper), * m. sternocleidomastoideus (sternocleidomastoid), * m. temporalis (temporal), * m. legator scapulae (levator scapula), * m. supraspinatus (supraspinatus), * m. suboccipitales (suboccipital).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Myofascial trigger points therapy increases neck mobility and reduces headache pain in migraine patients - pilot study.
Olesiejuk M, Chalimoniuk M, Sacewicz T. · · 2025 · cited 1× · PMID 39893364 · DOI 10.1186/s12891-025-08360-1
Verify or expand the search:
- PubMed search for NCT05646160
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT07336056 — Nerivio Efficacy Under High-Frequency Use · Phase 4 · active not recruiting
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Other Józef Piłsudski University of Physical Education trials
Trials by the same sponsor.
- NCT07061041 — Comparison of the Effects of Static Stretching and Full Range of Motion Strength Training on Posterior Band Flexibility · NA · recruiting
- NCT06960590 — Determining the Minimal Effective Dose of Static Stretching for Increasing Range of Motion in Adults · NA · active not recruiting
- NCT06821477 — Impact of Knee Extension Brace on Quadriceps EMG During ASLR · active not recruiting
- NCT06804564 — Cold Vs Warm Water Immersion for DOMS Recovery · NA · recruiting
- NCT06896773 — Effect of Training in Normobaric Hypoxia on Cardiac Markers · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05646160 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Józef Piłsudski University of Physical Education
- Last refreshed: 2 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05646160.
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