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NCT05643235
Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors
NA trial testing Medtronic LINQ-2 Insertable Cardiac Monitor (ILR) in Atrial Fibrillation in 50 participants. Currently enrolling.
1 December 2026
Quick facts
| Lead sponsor | Northwell Health |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 50 |
| Start date | 1 January 2023 |
| Primary completion | 1 December 2026 |
| Estimated completion | 1 December 2030 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Medtronic LINQ-2 Insertable Cardiac Monitor (ILR)
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
- Supraventricular Arrhythmia — all drugs for Supraventricular Arrhythmia →
- Ventricular Arrhythmias and Cardiac Arrest — all drugs for Ventricular Arrhythmias and Cardiac Arrest →
- Chronic Lymphocytic Leukemia — all drugs for Chronic Lymphocytic Leukemia →
Sponsor
Northwell Health — full company profile →
Who can join
18 and older, any sex, with Atrial Fibrillation or Supraventricular Arrhythmia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will enroll patients initiating Bruton Tyrosine Kinase (BTK) inhibitors without history of documented arrhythmia while on therapy using the Medtronic LINQ-2 insertable cardiac monitor (ILR). The incidence of new onset atrial fibrillation (AF) and other arrhythmia will be determined. Actions taken in response to device detected arrhythmia will be recorded.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05643235
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Northwell Health trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05643235 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Northwell Health
- Last refreshed: 18 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05643235.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing