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NCT05633199
Cytoreductive Surgery in Platinum-resistant Recurrent Ovarian Cancer
NA trial testing cytoreductive surgery in Cytoreductive Surgery in 140 participants. Not yet recruiting.
1 November 2026
Quick facts
| Lead sponsor | Women's Hospital School Of Medicine Zhejiang University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 140 |
| Start date | 1 December 2022 |
| Primary completion | 1 November 2026 |
| Estimated completion | 1 January 2028 |
| Sites | 2 locations across China |
Drugs / interventions tested
- cytoreductive surgery
Conditions studied
- Cytoreductive Surgery — all drugs for Cytoreductive Surgery →
Sponsor
Women's Hospital School Of Medicine Zhejiang University
Who can join
Adults 18 to 70, female only, with Cytoreductive Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This novel study was specifically designed for platinum-resistant recurrent ovarian cancers with PFI\<6 months and aimed to compare prognosis of patients who received cytoreductive surgery followed by chemotherapy versus chemotherapy alone.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Homologous recombination proficient subtypes of high-grade serous ovarian cancer: treatment options for a poor prognosis group.
Stiegeler N, Garsed DW, Au-Yeung G, Bowtell DDL, et al · · 2024 · cited 10× · PMID 38894867 · DOI 10.3389/fonc.2024.1387281 -
Platinum-resistant ovarian cancer in China: Practice and challenges.
Lin J, Li A, Liu L, Zhang L, et al · · 2026 · PMID 40908915 · DOI 10.1097/cm9.0000000000003763 -
Evaluation of secondary cytoreduction surgery in platinum-resistant ovarian cancer patients within three-line recurrent: a multicenter, randomized controlled study.
Chen T, Xu J, Xia B, Wang H, et al · · 2024 · PMID 37945326 · DOI 10.3802/jgo.2024.35.e22
Verify or expand the search:
- PubMed search for NCT05633199
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of cytoreductive surgery
Trials testing the same drug.
- NCT05610826 — Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver · Phase 1, PHASE2 · withdrawn
- NCT03373058 — Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery · Phase 3 · unknown
- NCT02399410 — Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis · Phase 2 · completed
Other recruiting trials for Cytoreductive Surgery
Currently open trials in the same condition.
- NCT05597683 — Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy · NA · recruiting
- NCT05316181 — CRS & HIPEC for Platinum-Resistant Recurrent Ovarian Cancer (KOV-02R, RECOVER) · Phase 3 · active not recruiting
Other Women's Hospital School Of Medicine Zhejiang University trials
Trials by the same sponsor.
- NCT07369986 — Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer · Phase 2 · not yet recruiting
- NCT07244965 — Neoadjuvant Ivonescimab Plus Chemotherapy Followed by Concurrent Chemoradiotherapy in High-Risk Locally Advanced Cervica · Phase 2 · not yet recruiting
- NCT06561308 — Clinical Efficacy Study of PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Advanced Endometrial Cancer · Phase 2 · recruiting
- NCT07106853 — Prenatal Cell-free DNA Screening in Pregnancies With Diverse Genetic Risk Profiles Utilizing Targeted and Whole-exome Se · not yet recruiting
- NCT07082530 — A RCT of Labor Induction at 39 Weeks in Low - Risk Women in China · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05633199 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Women's Hospital School Of Medicine Zhejiang University
- Last refreshed: 1 December 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05633199.
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