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NCT05627206: PM+FM
The Impact of PM+For Moms Intervention on Improving Mother's Mental Health in Zambia (PM+FM)
NA trial testing Problem Management + For Moms in Depressive Symptoms in 270 participants. Completed in 1 December 2023.
1 October 2023
Quick facts
| Lead sponsor | Swiss Tropical & Public Health Institute |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 270 |
| Start date | 15 November 2022 |
| Primary completion | 1 October 2023 |
| Estimated completion | 1 December 2023 |
| Sites | 1 location across Zambia |
Drugs / interventions tested
- Problem Management + For Moms
Conditions studied
- Depressive Symptoms — all drugs for Depressive Symptoms →
- Anxiety — all drugs for Anxiety →
- Trauma, Psychological — all drugs for Trauma, Psychological →
Sponsor
Swiss Tropical & Public Health Institute
Who can join
18 and older, female only, with Depressive Symptoms or Anxiety. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
CMHD are particularly prevalent among women, posing a major threat to their own and their children's wellbeing. Despite the high prevalence of CMHD and the existence of effective treatments, interventions supporting women living in low-resourced settings remain limited. This study builds on a parent study (Zamcharts NCT03991182), which identified a high prevalence of women with anxiety and/or depression. We propose to design, test, and validate a community-based intervention nested within the public primary health system in Zambia, to identify and treat women with mild-to-severe CMHDs.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Feasibility and acceptability of the Problem Management for Moms programme for improving maternal mental health in Zambia: an open-label trial.
Fink G, Melero-Dominguez M, Chembe M, de Vernisy-Romero D, et al · · 2024 · cited 2× · PMID 39515361 · DOI 10.1016/s2215-0366(24)00256-6 -
Testing the feasibility, acceptability, and exploring trends on efficacy of the problem management plus for moms: Protocol of a pilot randomized control trial.
Falgas-Bague I, Melero-Dominguez M, de Vernisy-Romero D, Tembo T, et al · · 2024 · cited 2× · PMID 38181004 · DOI 10.1371/journal.pone.0287269 -
Understanding the impact of the PM4M intervention on women's mental wellbeing in Zambia and lessons for implementation: a qualitative study.
de Vernisy-Romero D, Melero-Dominguez M, Fernandez-Rodriguez A, Musonda C, et al · · 2026 · PMID 42232997 · DOI 10.3389/fpsyt.2026.1686644 -
Testing the Feasibility, Acceptability and Effectiveness of the Problem Management Plus for Moms: Protocol of a Randomized Control Trial
Falgas-Bague I, Melero-Dominguez M, de Vernisy-Romero D, Tembo T, et al · · 2023 · DOI 10.1101/2023.06.04.23290945
Verify or expand the search:
- PubMed search for NCT05627206
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05627206 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Swiss Tropical & Public Health Institute
- Last refreshed: 30 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05627206.
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