NCT05621200 (SCAtACS) is a NA clinical trial of Transcranial stimulation over the cerebellar hemispheres in Ataxia, sponsored by Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia.

Who is sponsoring NCT05621200?

NCT05621200 is sponsored by Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia.

What drugs are being tested in NCT05621200?

Interventions in NCT05621200: Transcranial stimulation over the cerebellar hemispheres.

What condition does NCT05621200 study?

NCT05621200 studies Ataxia, Spinocerebellar Ataxias, Multiple System Atrophy, Ataxia With Oculomotor Apraxia, CANVAS.

Is NCT05621200 still recruiting?

NCT05621200 is currently completed. Last updated 27 December 2022.

Last reviewed 2022-12-27 · How we verify

NCT05621200: SCAtACS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Transcranial Alternating Current Stimulation (tACS) in Patients With Ataxia

Completed NA Last updated 27 December 2022

What this trial tests

NA trial testing Transcranial stimulation over the cerebellar hemispheres in Ataxia in 26 participants. Completed in 10 December 2022.

Timeline

28 January 2021

Primary endpoint
10 December 2022

10 December 2022

Quick facts

Lead sponsor	Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	treatment
Enrollment	26
Start date	28 January 2021
Primary completion	10 December 2022
Estimated completion	10 December 2022
Sites	1 location across Italy

Drugs / interventions tested

Transcranial stimulation over the cerebellar hemispheres

Conditions studied

Ataxia — all drugs for Ataxia →
Spinocerebellar Ataxias — all drugs for Spinocerebellar Ataxias →
Multiple System Atrophy — all drugs for Multiple System Atrophy →
Ataxia With Oculomotor Apraxia — all drugs for Ataxia With Oculomotor Apraxia →

Sponsor

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia — full company profile →

Who can join

18 and older, any sex, with Ataxia or Spinocerebellar Ataxias. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to evaluate the effects on motor and cognitive performance of transcranial alternating current stimulation (tACS) compared to transcranial direct current stimulation (tDCS) and placebo stimulation (sham) in patients with neurodegenerative ataxia to identify a possible rehabilitation protocol.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The Therapeutic Potential of Non-Invasive and Invasive Cerebellar Stimulation Techniques in Hereditary Ataxias.
Benussi A, Batsikadze G, França C, Cury RG, et al · · 2023 · cited 16× · PMID 37190102 · DOI 10.3390/cells12081193
Comparing Cerebellar tDCS and Cerebellar tACS in Neurodegenerative Ataxias Using Wearable Sensors: A Randomized, Double-Blind, Sham-Controlled, Triple-Crossover Trial.
Libri I, Cantoni V, Benussi A, Rivolta J, et al · · 2024 · cited 7× · PMID 37349632 · DOI 10.1007/s12311-023-01578-6

Verify or expand the search:

Other recruiting trials for Ataxia

Currently open trials in the same condition.

NCT06420271 — Effects of Cerebellar tACS-iTBS in Ataxia · NA · recruiting
NCT06585605 — A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia · recruiting
NCT05443906 — Home Exercise for Individuals with Neurodegenerative Disease · NA · recruiting
NCT06958341 — Neuroimmunology Registry and Biobank · recruiting
NCT03881930 — Balance Rehabilitation With Modified Visual Input in Patients With Neuropathy · NA · recruiting

Other Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia trials

Trials by the same sponsor.

NCT06493708 — Effectiveness of EMDR in Borderline Personality Disorder · NA · recruiting
NCT07370961 — Pilot Study to Evaluate the Impact of a Multidisciplinary Approach (Pharmacological and Psychological) in the Treatment · NA · completed
NCT05847387 — The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study · recruiting
NCT05738902 — Adherence and Compliance to ERAS in Gynecological Surgery · unknown
NCT06765343 — Efficacy of Guided Biofilm Therapy in Pediatric Patient · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05621200 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Last refreshed: 27 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05621200.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing