NCT05619419

Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates

Completed NA Last updated 22 March 2023

What this trial tests

NA trial testing Mindfulness-enhanced positive affect induction in Meditation in 180 participants. Completed in 14 November 2022.

Timeline

14 March 2022

Primary endpoint
14 November 2022

14 November 2022

Quick facts

Lead sponsor	University of Colorado, Denver
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	none
Primary purpose	other
Enrollment	180
Start date	14 March 2022
Primary completion	14 November 2022
Estimated completion	14 November 2022
Sites	1 location across United States

Drugs / interventions tested

• Mindfulness-enhanced positive affect induction
• Breathing Meditation

Conditions studied

• Meditation — all drugs for Meditation →
• Pain — all drugs for Pain →
• Mindfulness — all drugs for Mindfulness →
• Affect — all drugs for Affect →

Sponsor

University of Colorado, Denver

Who can join

Adults 18 to 65, any sex, with Meditation or Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to test if a mindfulness-enhanced positive affect induction (MPAI) works well to reduce pain intensity and pain unpleasantness from a cold water pain test in undergraduate college students who do not endorse ongoing medical or mental health diagnoses. The main questions it aims to answer are:

* Is the MPAI a feasible and acceptable psychological technique for managing brief pain?
* Does the MPAI work well to reduce pain intensity and unpleasantness from experimentally induced brief pain, compared to those using a breathing meditation or those instructed to respond naturally.
* Does using the MPAI work well to improve confidence in self-managing brief pain?

Participants will be asked to complete questionnaires about their sleep, pain beliefs, and emotions after consenting to participate and at the end of the study session. They will then be randomized to either:

* Use the MPAI for managing pain induced by a cold water test (placing their hand in a container of cold water kept at approximately 5 degrees Celsius).
* Use a breathing meditation for managing pain induced by a cold water test (placing their hand in a container of cold water kept at approximately 5 degrees Celsius).
* Respond naturally to pain induced by a cold water test (placing their hand in a container of cold water kept at approximately 5 degrees Celsius).

Researchers will compare the MPAI group to the breathing meditation and natural response groups to see if the MPAI group reports less pain from the cold water test and

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.