NCT05619211

Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities

Completed Phase 1 Results posted Last updated 2 April 2026

What this trial tests

Phase 1 trial testing Sprint-Intensity Interval Training with Telecoaching in Cerebral Palsy in 42 participants. Completed in 18 December 2025.

Timeline

29 September 2023

Primary endpoint
1 November 2025

18 December 2025

Quick facts

Lead sponsor	University of Alabama at Birmingham
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	42
Start date	29 September 2023
Primary completion	1 November 2025
Estimated completion	18 December 2025
Sites	1 location across United States

Drugs / interventions tested

• Sprint-Intensity Interval Training with Telecoaching

Conditions studied

• Cerebral Palsy — all drugs for Cerebral Palsy →

Sponsor

University of Alabama at Birmingham

Who can join

Adults 6 to 17, any sex, with Cerebral Palsy. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Changes in pVO2 Primary · Week 0, Week 13

peak oxygen consumption (mL/kg-1/min-1) obtained from a graded exercise test on an arm ergometer. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	1.72	0.52 – 2.91
Wait-list Control	-0.61	-1.77 – 0.55

Change in Body Weight Secondary · Week 0, Week 13

body weight in kg measured via DXA scan. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	0.53	-0.60 – 1.66
Wait-list Control	1.38	0.28 – 2.47

Changes in Total Body Fat Secondary · Week 0, Week 13

body fat in kg measured via DXA scan. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	0.03	-0.99 – 1.05
Wait-list Control	1.22	0.24 – 2.21

Changes in Total Lean Mass Secondary · Week 0, Week 13

lean mass in kg measured via DXA scan. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	0.47	-3.50 – 4.43
Wait-list Control	3.07	-0.77 – 6.91

Changes in Lean Tissue Percentage Secondary · Week 0, Week 13

percentage of lean tissue per whole body weight. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	0.81	-0.30 – 1.93
Wait-list Control	-0.21	-1.29 – 0.88

Changes in Fat Tissue Percentage Secondary · Week 0, Week 13

percentage of fat tissue per whole body weight. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	-0.23	-2.68 – 2.22
Wait-list Control	1.72	-0.66 – 4.09

Changes in C-reactive Protein Secondary · Week 0, Week 13

hsCRP (mg/L) measured via dried blood spot test. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	-0.29	-1.85 – 1.26
Wait-list Control	0.31	-1.12 – 1.75

Changes in Hemoglobin A1C Secondary · Week 0, Week 13

HbA1C (mmol/mol) measured via dried blood spot test. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	0.10	-0.15 – 0.36
Wait-list Control	0.08	-0.18 – 0.32

Changes in Fasting Insulin Secondary · Week 0, Week 13

Fasting Insulin (μIU/mL) measured via dried blood spot test. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	-6.61	-10.98 – -2.23
Wait-list Control	-0.95	-5.39 – 3.49

Changes in Fasting Triglycerides Secondary · Week 0, Week 13

Fasting Triglycerides (mg/dL) measured via dried blood spot test. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	-12.93	-30.06 – 4.20
Wait-list Control	4.63	-12.20 – 21.45

Changes in Fasting High-density Lipoprotein Secondary · Week 0, Week 13

HDL cholesterol (mg/dL) measured via dried blood spot test. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	-6.46	-12.38 – -0.53
Wait-list Control	-2.63	-8.37 – 3.12

Changes in Fasting Low-density Lipoprotein Secondary · Week 0, Week 13

LDL cholesterol (mg/dL) measured via dried blood spot test. Data represents the child participant. Outcome measures were not collected for the parent participant.

Group	Value	95% CI
Movement-to-Music	-15.10	-32.48 – 2.29
Wait-list Control	0.94	-15.56 – 17.44

Sponsor's own description

This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and age-appropriate themes. This project has the potential to address a large knowledge gap in the extant literature, because there are no widely accessible, evidence-based, enjoyable, and age-appropriate modalities for improving cardiovascular fitness or cardiometabolic health among children with disabilities who have mobility disabilities.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Telehealth Movement-to-Music With Arm-Based Sprint-Intensity Interval Training to Improve Cardiometabolic Health and Cardiorespiratory Fitness in Children With Cerebral Palsy: Protocol for a Pilot Randomized Controlled Trial.
   Lai B, Oster RA, Davis D, Bright L, et al · · 2024 · PMID 38441939 · DOI 10.2196/56499