Who is sponsoring NCT05597774?

NCT05597774 is sponsored by Universidad Complutense de Madrid.

What drugs are being tested in NCT05597774?

Interventions in NCT05597774: Inspiratory + expiratory muscle training group, Inspiratory + expiratory muscle training sham group, Exercise training program.

What condition does NCT05597774 study?

NCT05597774 studies Covid19, Post-acute COVID-19 Syndrome.

Is NCT05597774 still recruiting?

NCT05597774 is currently completed. Last updated 28 September 2023.

Last reviewed 2023-09-28 · How we verify

NCT05597774

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Respiratory Muscle Training in Individuals With Long-term Post-COVID-19 Symptoms

Completed NA Last updated 28 September 2023

What this trial tests

NA trial testing Inspiratory + expiratory muscle training group in Covid19 in 64 participants. Completed in 22 September 2023.

Timeline

28 October 2022

Primary endpoint
22 September 2023

22 September 2023

Quick facts

Lead sponsor	Universidad Complutense de Madrid
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	64
Start date	28 October 2022
Primary completion	22 September 2023
Estimated completion	22 September 2023
Sites	1 location across Spain

Drugs / interventions tested

Inspiratory + expiratory muscle training group
Inspiratory + expiratory muscle training sham group
Exercise training program

Conditions studied

Covid19 — all drugs for Covid19 →
Post-acute COVID-19 Syndrome — all drugs for Post-acute COVID-19 Syndrome →

Sponsor

Universidad Complutense de Madrid — full company profile →

Who can join

Adults 18 to 100, any sex, with Covid19 or Post-acute COVID-19 Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main objective of the present study is to observe the short-term effects of respiratory muscle training combined with an exercise training program on quality of life and exercise tolerance in individuals with long-term post-COVID-19 symptoms. As secondary objectives, the effects on respiratory muscle function, physical and lung function, as well as on the psychological state of these individuals.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of respiratory rehabilitation on quality of life in individuals with post-COVID-19 symptoms: A randomised controlled trial.
Del Corral T, Fabero-Garrido R, Plaza-Manzano G, Izquierdo-García J, et al · · 2025 · cited 6× · PMID 39798250 · DOI 10.1016/j.rehab.2024.101920

Verify or expand the search:

Other trials of Inspiratory + expiratory muscle training group

Trials testing the same drug.

NCT04734561 — Effects of Respiratory Muscle Training in People Who Have Had COVID-19 Disease · NA · completed

Other recruiting trials for Covid19

Currently open trials in the same condition.

NCT03305341 — Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologic Mix · EARLY_PHASE1 · active not recruiting
NCT06482138 — Dysfunction of Olfaction After COVID-19 Infection: Morphological and Histomolecular Investigation · NA · recruiting
NCT04924803 — Community Developed Technology-Based Messaging to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs · NA · active not recruiting
NCT05013632 — COVID-19 International Drug Pregnancy Registry · recruiting
NCT04806061 — Urine Alkalinisation in COVID-19 · NA · active not recruiting

Other Universidad Complutense de Madrid trials

Trials by the same sponsor.

NCT07361848 — Long-Hold Yielding Isometric Exercise for Patellar Tendinopathy in Weightlifting Athletes · NA · not yet recruiting
NCT07273006 — Percutaneous Electrical Nerve Stimulation As Alternative To Nerve Blocks In Anesthesia, Pain Medicine And Rehabilitation · Phase 4 · not yet recruiting
NCT07527351 — ANALYSIS OF THE RELIABILITY AND VALIDITY OF LASER SPECKLE CONTRAST IMAGING · NA · recruiting
NCT07484620 — Physical Activity and Fitness in Pediatric Inflammatory Bowel Disease · NA · not yet recruiting
NCT07485400 — Aerobic Interval vs Continuous Training on Heart Rate-Power Decoupling in Ischemic Heart Disease · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05597774 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidad Complutense de Madrid
Last refreshed: 28 September 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05597774.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing