NCT04734561

Effects of Respiratory Muscle Training in People Who Have Had COVID-19 Disease

Completed NA Last updated 30 September 2021

What this trial tests

NA trial testing Inspiratory muscle training group in Covid19 in 88 participants. Completed in 29 September 2021.

Timeline

8 February 2021

Primary endpoint
31 July 2021

29 September 2021

Quick facts

Lead sponsor	Universidad Complutense de Madrid
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	88
Start date	8 February 2021
Primary completion	31 July 2021
Estimated completion	29 September 2021
Sites	1 location across Spain

Drugs / interventions tested

• Inspiratory muscle training group
• Inspiratory muscle training placebo group
• Inspiratory + expiratory muscle training group
• Inspiratory + expiratory muscle training placebo group

Conditions studied

• Covid19 — all drugs for Covid19 →
• Respiratory Muscle Training — all drugs for Respiratory Muscle Training →
• Respiratory Function Test — all drugs for Respiratory Function Test →
• Quality of Life — all drugs for Quality of Life →

Sponsor

Universidad Complutense de Madrid — full company profile →

Who can join

18 and older, any sex, with Covid19 or Respiratory Muscle Training. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main objective of the present study is to observe the short-term effects of respiratory muscle training applied by telerehabilitation on quality of life and exercise tolerance in people who have had the COVID-19 disease. As secondary objectives, the effects on respiratory muscles strength/tolerance, pulmonary function and psychological and cognitive factors.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Home-based respiratory muscle training on quality of life and exercise tolerance in long-term post-COVID-19: Randomized controlled trial.
   Del Corral T, Fabero-Garrido R, Plaza-Manzano G, Fernández-de-Las-Peñas C, et al · · 2023 · cited 86× · PMID 36191860 · DOI 10.1016/j.rehab.2022.101709
2. Minimal Clinically Important Differences in EQ-5D-5L Index and VAS after a Respiratory Muscle Training Program in Individuals Experiencing Long-Term Post-COVID-19 Symptoms.
   Del Corral T, Fabero-Garrido R, Plaza-Manzano G, Navarro-Santana MJ, et al · · 2023 · cited 32× · PMID 37760964 · DOI 10.3390/biomedicines11092522
3. Minimal Clinically Important Differences in Inspiratory Muscle Function Variables after a Respiratory Muscle Training Programme in Individuals with Long-Term Post-COVID-19 Symptoms.
   Del Corral T, Fabero-Garrido R, Plaza-Manzano G, Fernández-de-Las-Peñas C, et al · · 2023 · cited 18× · PMID 37048804 · DOI 10.3390/jcm12072720