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NCT05596435

Early Detection of Pancreatic Cancer

Status unknown Last updated 27 October 2022
What this trial tests

trial testing No intervention in Pancreatic Cancer in 496 participants. Status unknown.

Timeline
10 October 2022
Primary endpoint
12 October 2023
12 October 2024

Quick facts

Lead sponsorTianjin Medical University Cancer Institute and Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment496
Start date10 October 2022
Primary completion12 October 2023
Estimated completion12 October 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Tianjin Medical University Cancer Institute and Hospital

Who can join

Adults 18 to 75, any sex, with Pancreatic Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to enable non-invasive early detection of pancreatic cancer in high-risk populations through the establishment of a machine learning model using plasma cell-free DNA fragmentomics. Plasma cell-free DNA from early stage pancreatic cancer patients and healthy individuals will be subjected to whole-genome sequencing. Features, such as cell-free DNA fragmentation, copy number variations and the status of KRAS gene mutation, will be assessed to generate this model.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Exploring the clinical utility of liquid biopsy with cfDNA in cancer: A systematic review.
    Ranganathan K, Kurian NS, Goswami HM, Rishi KD, et al · · 2024 · cited 5× · PMID 40027943 · DOI 10.1016/j.jlb.2024.100150

Verify or expand the search:

Other trials of No intervention

Trials testing the same drug.

Other recruiting trials for Pancreatic Cancer

Currently open trials in the same condition.

Other Tianjin Medical University Cancer Institute and Hospital trials

Trials by the same sponsor.

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Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05596435.

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