NCT05592054 (PROTECT-MT) is a NA clinical trial of Balloon guide catheters (BGCs) in Acute Ischemic Stroke, sponsored by Changhai Hospital.

Who is sponsoring NCT05592054?

NCT05592054 is sponsored by Changhai Hospital.

What drugs are being tested in NCT05592054?

Interventions in NCT05592054: Balloon guide catheters (BGCs), Standard guide catheter.

What condition does NCT05592054 study?

NCT05592054 studies Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis.

Is NCT05592054 still recruiting?

NCT05592054 is currently terminated. Last updated 16 July 2024.

Last reviewed 2024-07-16 · How we verify

NCT05592054: PROTECT-MT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Proximal TEmporary oCclusion Using Balloon Guide Catheter for Mechanical Thrombectomy

Terminated NA Last updated 16 July 2024

What this trial tests

NA trial testing Balloon guide catheters (BGCs) in Acute Ischemic Stroke in 329 participants. Terminated before completion.

Timeline

7 February 2023

Primary endpoint
25 March 2024

25 March 2024

Quick facts

Lead sponsor	Changhai Hospital
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	329
Start date	7 February 2023
Primary completion	25 March 2024
Estimated completion	25 March 2024
Sites	1 location across China

Drugs / interventions tested

Balloon guide catheters (BGCs)
Standard guide catheter

Conditions studied

Acute Ischemic Stroke — all drugs for Acute Ischemic Stroke →
Large Vessel Occlusion — all drugs for Large Vessel Occlusion →
Thrombectomy — all drugs for Thrombectomy →
Thrombosis — all drugs for Thrombosis →

Sponsor

Changhai Hospital

Who can join

18 and older, any sex, with Acute Ischemic Stroke or Large Vessel Occlusion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A multi-center, prospective, randomized, open-label, blinded endpoint assessment (PROBE) clinical trial of endovascular treatment among selected AIS.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Balloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial.
Liu J, Zhou Y, Zhang L, Li Z, et al · · 2024 · cited 25× · PMID 39579782 · DOI 10.1016/s0140-6736(24)02315-8

Verify or expand the search:

Other recruiting trials for Acute Ischemic Stroke

Currently open trials in the same condition.

NCT07115940 — Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours · NA · recruiting
NCT07404852 — Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemi · NA · recruiting
NCT07361302 — A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Pe · Phase 3 · recruiting
NCT07436156 — SUMMIT RISE Study of Acute Ischemic Stroke Patients · Phase 4 · recruiting
NCT07203625 — Tenecteplase Before Interhospital Transfer in Acute Basilar Artery Occlusion at 4.5 to 24 Hours · Phase 4 · recruiting

Other Changhai Hospital trials

Trials by the same sponsor.

NCT07490002 — Neoadjuvant Therapy With Iparomlimab and Tuvonralimab, Lenvatinib and Chemotherapy in Resectable ESCC · Phase 2 · not yet recruiting
NCT07464392 — FMT for the Prevention of Infectious Complications in Patients With Moderately Severe and Severe Acute Pancreatitis · NA · recruiting
NCT07507071 — Comparison of the Sensitivity of pCLE and Pathological Biopsy for Gastric Mucosal Lesions · not yet recruiting
NCT07481591 — Capsule Endoscopy in GI Bleeding: A Retrospective Study · not yet recruiting
NCT07439757 — AI-Powered Precision Decision-Making for Pancreatic Diseases · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05592054 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Changhai Hospital
Last refreshed: 16 July 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05592054.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing