Last reviewed · How we verify
NCT05588544
YSGG Application in Periodontal Treatment
NA trial testing Er,Cr:YSGG laser in Periodontal Diseases in 12 participants. Completed in 29 June 2021.
29 June 2021
Quick facts
| Lead sponsor | Korea University Anam Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 12 |
| Start date | 26 May 2020 |
| Primary completion | 29 June 2021 |
| Estimated completion | 29 June 2021 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Er,Cr:YSGG laser
Conditions studied
- Periodontal Diseases — all drugs for Periodontal Diseases →
Sponsor
Korea University Anam Hospital
Who can join
Eligibility, any sex, with Periodontal Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Adjunctive use of Er,Cr:YSGG (erbium-chromium-yttrium-scandium-gallium-garnet) laser in combination with conventional, mechanical periodontal treatment may benefit in complete decontamination of the periodontal pocket leading to improved early healing and better long term clinical result. Radial firing periodontal tip (RFPT) offered by the Er,Cr:YSGG system is devised to let irradiation primarily in radial pattern (85%) with lesser portion in straight manner (15%), meaning laser beams are effectively emitted to affected root surface and inner epithelium of periodontal pocket with simple tip management. Therefore, using Er,Cr:YSGG laser with RFPT could be the best option for periodontal laser therapy. The aim of this study is to investigate adjunctive treatment effect using Er,Cr:YSGG laser and RFPT in moderate to severe periodontitis patients. Study subjects are randomly allocated to either 'scaling and root planing (SRP) only' or 'SRP + laser therapy' group. Periodontal parameters including probing pocket depth (PPD), clinical attachment level (CAL), modified gingival index (MGI), and plaque index (PI) are recorded at baseline and 8 weeks after treatment. Gingival crevicular fluid (GCF) samples are obtained using paper strips at baseline, 1w, 2w, 4w, and 8w post op. to determine laser-induced effect in early wound healing. Cytokine levels are evaluated from the GCF samples taken.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of erbium, chromium-doped: yttrium, scandium, gallium, and garnet laser-assisted periodontal therapy using radial firing tip during early healing period: a randomized controlled split-mouth clinical trial.
Park JS, Jung H, Ryu JJ, Koo KT, et al · · 2024 · cited 2× · PMID 38720276 · DOI 10.1186/s12903-024-04270-1
Verify or expand the search:
- PubMed search for NCT05588544
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Er,Cr:YSGG laser
Trials testing the same drug.
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- NCT07520266 — Gingival Depigmentation With Diode and Er,Cr:YSGG Laser: A Split-mouth Trial · NA · completed
- NCT06002646 — Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy Techniques · Phase 4 · completed
- NCT03544515 — Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase · NA · completed
- NCT03233165 — Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral Leukoplakia · NA · completed
Other recruiting trials for Periodontal Diseases
Currently open trials in the same condition.
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- NCT07384221 — Periodontal Status and Disease Severity in Pemphigus Vulgaris Patients · recruiting
- NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
- NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting
Other Korea University Anam Hospital trials
Trials by the same sponsor.
- NCT07510932 — Fruquintinib In Patients With Metastatic Colorectal Cancer Refractory to Standard Chemotherapies in South Korea Patients · Phase 2 · not yet recruiting
- NCT07280780 — CGM-Based Glycemic Analysis After ESI · not yet recruiting
- NCT07189000 — Patient-centered REhabilitation Program to Advance REcovery · NA · not yet recruiting
- NCT07246148 — NOn-inVAsive Blood Pressure Monitoring in Intracranial Aneurysm Embolization · NA · recruiting
- NCT07376980 — The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05588544 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Korea University Anam Hospital
- Last refreshed: 20 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05588544.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing