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NCT05582317
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
NA trial testing Biodentine in Pulpitis - Irreversible in 20 participants. Completed in 25 July 2022.
24 May 2022
Quick facts
| Lead sponsor | Suez Canal University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 23 May 2021 |
| Primary completion | 24 May 2022 |
| Estimated completion | 25 July 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Biodentine — full drug profile →
- Simvastatin (simvastatin) — full drug profile →
Conditions studied
- Pulpitis - Irreversible — all drugs for Pulpitis - Irreversible →
Sponsor
Suez Canal University
Who can join
Adults 4 to 7, any sex, with Pulpitis - Irreversible. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically. Study design: 60 primary molars in 20 children aged 4-7 years old were randomly allocated to three groups, Biodentine, Simvastatin and combination of Biodentine and simvastatin. Clinical and radiographic examinations were conducted at 1, 3, 6, 9 and 12 months after treatment. Key words: Pulpotomy, Primary teeth, Biodentine, Simvastatin.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05582317
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Biodentine
Trials testing the same drug.
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- NCT07130214 — The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy · active not recruiting
- NCT06695208 — Socket Preservation Using Biodentin Versus Xeno Graft for Single Rooted Teeth · Phase 4 · recruiting
- NCT05937100 — New Vital Pulpotomy Medications in Primary Molars · NA · active not recruiting
- NCT06020911 — Indirect Pulp Capping Using Biodentine and Theracal Light-cured in Primary Molars · Phase 4 · completed
Other recruiting trials for Pulpitis - Irreversible
Currently open trials in the same condition.
- NCT07245004 — Effect of Cryotherapy on Postoperative Pain for Pulpotomy · EARLY_PHASE1 · active not recruiting
- NCT07340606 — The Role of the Pre-operative Condition and Artificial Intelligence-Assisted Diagnosis in Predicting the Success of Full · NA · recruiting
- NCT07375576 — Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis · NA · recruiting
- NCT07306533 — Effect of Menstrual Phase on the Anesthetic Efficacy · NA · recruiting
- NCT07130214 — The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy · active not recruiting
Other Suez Canal University trials
Trials by the same sponsor.
- NCT07263893 — Inter Flex Three Dimensional Plate in Management of Mandibular Fracture RCT · NA · recruiting
- NCT07280533 — Accuracy of Virtual Surgical Planning Versus Traditional Technique in Zygomaticomaxillary Fracture Reduction · NA · not yet recruiting
- NCT07291791 — tDCS for Pain Modulation in Knee Osteoarthritis · NA · active not recruiting
- NCT07262086 — Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite · NA · enrolling by invitation
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05582317 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Suez Canal University
- Last refreshed: 17 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05582317.
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