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NCT07262086
Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite
NA trial testing Resins, Composite nanohybrid in Dental Caries in 25 participants. Enrolling by invitation.
2 December 2026
Quick facts
| Lead sponsor | Suez Canal University |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 25 |
| Start date | 22 November 2025 |
| Primary completion | 2 December 2026 |
| Estimated completion | 30 December 2027 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Resins, Composite nanohybrid
- Resins, Composite bioactive
Conditions studied
- Dental Caries — all drugs for Dental Caries →
- Class II Dental Caries — all drugs for Class II Dental Caries →
Sponsor
Suez Canal University
Who can join
Adults 21 to 45, any sex, with Dental Caries or Class II Dental Caries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Resin-based composites (RBCs) have become the gold standard in restorative dentistry due to their superior aesthetics, adhesion, and minimally invasive application. However, wear remains a critical drawback, compromising their longevity and clinical performance. Various techniques have been suggested to measure the clinical performance of (RBCs). Recent advancements in digital dentistry, such as intraoral scanning, offer a more precise and efficient approach for quantitative wear assessment. Aim: This study aims to evaluate wear resistance and bioactivity of self cured bioactive resin composite vs nanhybrid resin composite. Methodology: Twelve healthy patients with 24 carious molar teeth will be selected where each patient should have two oclusso- mesial cavities. Standardized oclusso- mesial cavities will be prepared for all the selected teeth, for each patient the first tooth will be restored with conventional nanohybrid RBC (M1). Meanwhile, the second tooth will be restored by self-cure bioactive RBC (M2). Then, wear resistance will be evaluated by intraoral scanner immediately after restoration (T0), six months later (T1), after 12 months (T2), 18 months (T3) and 24 months (T4). Software analysis will be done by superimposing the 3D digital impression and evaluate the restoration wear by calculating the 3D volume loss. Also, bioactivity of the restoration will be measured by measuring the mineral density beneath the restoration. Digital radiographic images will be taken for the restoration by parallel technique and grey scale of the pixels under restoration will be measured by software immediately after restoration (D0), one month later (D1) and after 3 months (D2).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07262086
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07262086 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Suez Canal University
- Last refreshed: 22 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07262086.
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