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NCT05579808
Effect of Epidural Analgesia on Labour, Neonatal and Maternal Outcomes.
trial testing Epidural Analgesia in Labor Pain in 21,808 participants. Completed in 1 September 2021.
1 July 2021
Quick facts
| Lead sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 21,808 |
| Start date | 1 June 2021 |
| Primary completion | 1 July 2021 |
| Estimated completion | 1 September 2021 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Epidural Analgesia — full drug profile →
Conditions studied
- Labor Pain — all drugs for Labor Pain →
- Delivery Complication — all drugs for Delivery Complication →
- Regional Anesthesia Morbidity — all drugs for Regional Anesthesia Morbidity →
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Who can join
Eligibility, female only, with Labor Pain or Delivery Complication. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lumbar epidural analgesia is the most used method for reducing labour pain, but its impact on the duration of the second stage of labour and on neonatal and maternal outcomes remains debated. The aim was of the study is to examine whether epidural analgesia affects the course and the outcomes of labour among patients divided according to the Robson-10 group classification system. Patients of Robson's classes 1, 2a, 3, and 4a were divided into either the epidural analgesia group or the non-epidural analgesia group. A propensity score matching analysis was performed to balance intergroup differences. The primary goal was to analyse the duration of the second stage of labour. The secondary goals were to evaluate neonatal and maternal outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05579808
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Epidural Analgesia
Trials testing the same drug.
- NCT07077785 — The Effects of Epidural Analgesia on Maternal-Infant Bonding and Birth-Related Trauma · NA · not yet recruiting
- NCT06860854 — EPidural's Impact on Contractions and Fetal REsponse · not yet recruiting
- NCT06772545 — Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery · NA · not yet recruiting
- NCT06779968 — Multimodal Analgesia Versus Peripheral Nerve Block for Postoperative Pain Management After Lower Limb Injury Surgery · NA · not yet recruiting
- NCT04945512 — Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma · NA · unknown
Other recruiting trials for Labor Pain
Currently open trials in the same condition.
- NCT07440069 — Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active Labor · Phase 4 · recruiting
- NCT07411352 — Left Lateral Position vs Supine Position to Reduce Active Labor Duration · NA · recruiting
- NCT07401147 — Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Labor. · NA · recruiting
- NCT07395934 — Comparing PIEB and CEI for Labor Pain Relief · NA · recruiting
- NCT06819579 — Exploring the Optimal Concentration of Lidocaine Test Dose for Labor Analgesia · NA · active not recruiting
Other Fondazione Policlinico Universitario Agostino Gemelli IRCCS trials
Trials by the same sponsor.
- NCT07514572 — Impact of Estimated Weight and Height on Nutritional Assessment in Elderly · NA · not yet recruiting
- NCT07504679 — Adipose Visceral and Epicardial Risk Evaluation · NA · not yet recruiting
- NCT07520643 — MISTIC Study: Atherosclerosis, Neurocognition & Cardiovascular Signaling · not yet recruiting
- NCT07479238 — Breath Test-Based Assessment of SIBO in Chronic Pancreatitis and Partial Pancreatectomy · not yet recruiting
- NCT07494227 — Development of the SC-IBD Self-Care Measurement Scale · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05579808 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Last refreshed: 14 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05579808.
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