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Epidural analgesia
Epidural analgesia delivers pain-relieving medication directly into the epidural space around the spinal cord to block pain signals in a localized region.
Epidural analgesia delivers pain-relieving medication directly into the epidural space around the spinal cord to block pain signals in a localized region. Used for Perioperative pain management, Labor analgesia, Postoperative pain relief.
At a glance
| Generic name | Epidural analgesia |
|---|---|
| Also known as | No other intervention, Epidural Block, ropivicaine, hydromorphone, Naropin |
| Sponsor | Peking University First Hospital |
| Drug class | Regional anesthetic technique / Local anesthetic with or without opioid |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Anesthesia |
| Phase | Phase 3 |
Mechanism of action
Epidural analgesia involves injection of local anesthetics and/or opioids into the epidural space, which surrounds the dura mater of the spinal cord. The medication diffuses across the dura to block nerve roots and spinal cord segments, providing regional anesthesia and analgesia without affecting consciousness. This technique is commonly used for perioperative pain management, labor analgesia, and chronic pain conditions.
Approved indications
- Perioperative pain management
- Labor analgesia
- Postoperative pain relief
- Chronic pain conditions
Common side effects
- Hypotension
- Headache
- Urinary retention
- Pruritus
- Nausea
- Epidural hematoma
- Infection/epidural abscess
Key clinical trials
- Examining Analgesic Synergy and Efficacy in Trauma Care (PHASE4)
- Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
- Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy (PHASE4)
- Genicular Nerve Block Added to Femoral Nerve Block for Analgesia After Total Knee Arthroplasty (NA)
- Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (NA)
- Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy (PHASE4)
- Determinants of Clinical Outcome After Caudal Epidural Adhesiolysis for Chronic Lumbar Radicular Pain
- Evaluating the Effectiveness of Postoperative Analgesic Methods in Thoracotomy Cases
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Epidural analgesia CI brief — competitive landscape report
- Epidural analgesia updates RSS · CI watch RSS
- Peking University First Hospital portfolio CI