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NCT05576857
Effects of Cervical Hyperextension on Cervical Blood Flow, Cerebral Oximetry and Cognitive Functions.
trial testing Doppler ultrasonography in Hyperextension Injury of Neck in 55 participants. Completed in 20 March 2024.
20 March 2024
Quick facts
| Lead sponsor | Duzce University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 55 |
| Start date | 29 March 2021 |
| Primary completion | 20 March 2024 |
| Estimated completion | 20 March 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Doppler ultrasonography
Conditions studied
- Hyperextension Injury of Neck — all drugs for Hyperextension Injury of Neck →
Sponsor
Duzce University
Who can join
Adults 18 to 65, any sex, with Hyperextension Injury of Neck. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to determine the effects of cervical hyperextension on cerebral oximetry and cognitive functions in healthy individuals without other additional factors such as anesthesia and surgical stress. The main questions it aims to answer are: * Can cervical hyperextension cause changes in cerebral oxygenation in non-anesthetized healthy individuals? * Can cervical hyperextension cause changes in cervical and cerebral blood flow in non-anesthetized healthy individuals? * Can cervical hyperextension cause changes in cognitive functions in non-anesthetized healthy individuals? * Can cervical hyperextension cause changes in optic nerve sheath diameter in non-anesthetized healthy individuals? Participants will be monitored with cerebral oximeter device and asked to answer Montreal cognitive function test before and during cervical hyperextension position. The researchers will evaluate the changes in cervical and cerebral blood flow ultrasonographically before and during cervical hyperextension position.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Cervical Hyperextension Causes Acute Cerebral Congestion in Non-Anesthetized Healthy Adults: An Observational Self-Controlled Design Study.
Ersoy Karka O, Guclu D, Yorulmaz IS, Sungur MA, et al · · 2025 · PMID 41155778 · DOI 10.3390/medicina61101791
Verify or expand the search:
- PubMed search for NCT05576857
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05576857 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Duzce University
- Last refreshed: 7 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05576857.
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