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NCT05575583
rTMS in the Prevention and Treatment of Postoperative Executive Dysfunction
NA trial testing repetitive transcranial magnetic stimulation in Executive Function Disorder in 400 participants. Status unknown.
30 July 2025
Quick facts
| Lead sponsor | Xuzhou Central Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 400 |
| Start date | 30 November 2022 |
| Primary completion | 30 July 2025 |
| Estimated completion | 30 September 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- repetitive transcranial magnetic stimulation
- pseudo repetitive transcranial magnetic stimulation
Conditions studied
- Executive Function Disorder — all drugs for Executive Function Disorder →
- Functional Magnetic Resonance Imaging — all drugs for Functional Magnetic Resonance Imaging →
Sponsor
Xuzhou Central Hospital
Who can join
Adults 45 to 75, any sex, with Executive Function Disorder or Functional Magnetic Resonance Imaging. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Repetitive transcranial magnetic stimulation (rTMS) is a new neuroelectrophysiological technique developed in recent years. rTMS can affect local and distant cortical function, promote regional reconstruction of cortical function, and has clear curative effect on a variety of neuropsychiatric diseases. Previous study found that rTMS can improve postoperative cognitive function, and there may be a dual biological mechanism. Brain network abnormalities may be the direct cause of postoperative cognitive dysfunction, and neuroinflammation is one of the key molecular mechanisms behind postoperative cognitive dysfunction . rTMS may play a role in the regulation of brain network and inflammatory molecules, and thus play a role in the prevention and treatment of postoperative cognitive dysfunction (POCD).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05575583
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06451809 — Prediction of the Response to a Course of Transcranial Magnetic Stimulation (rTMS) Based on Heart Rate Variability · suspended
Other recruiting trials for Executive Function Disorder
Currently open trials in the same condition.
- NCT06604000 — Goal Management Training (GMT) for Improvement of Cognitive Control Function After Acquired Brain Injury · NA · recruiting
- NCT06369714 — Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children. · NA · recruiting
Other Xuzhou Central Hospital trials
Trials by the same sponsor.
- NCT06126289 — CSF Single-cell Sequencing and Proteomics of Chronic Postsurgical Pain in Patients With Lower Limb Fractures · unknown
- NCT06136663 — Prevalence and Risk Factors for Postsurgical Pain After the Open Reduction and Internal Fixation of Lower Limbs. · unknown
- NCT06050096 — DCB Treatment in CTO Guided by IVUS · unknown
- NCT06395961 — Effect of New High Ankle Block on Wound Healing After the Operation of Debridement of Diabetes Foot · NA · enrolling by invitation
- NCT05772026 — Plasma Proteomics in Patients With Postoperative Delirium · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05575583 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Xuzhou Central Hospital
- Last refreshed: 8 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05575583.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing