Last reviewed · How we verify
NCT05574699
Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
NA trial testing Social Risk Score and CDS Tool in Chronic Disease in 251 participants. Completed in 27 May 2025.
27 May 2025
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 251 |
| Start date | 30 April 2023 |
| Primary completion | 27 May 2025 |
| Estimated completion | 27 May 2025 |
| Sites | 5 locations across United States |
Drugs / interventions tested
- Social Risk Score and CDS Tool
- Standard of Care
Conditions studied
- Chronic Disease — all drugs for Chronic Disease →
- Diabetes Mellitus — all drugs for Diabetes Mellitus →
- Hypertension — all drugs for Hypertension →
- Congestive Heart Failure — all drugs for Congestive Heart Failure →
Sponsor
Johns Hopkins University
Who can join
18 and older, any sex, with Chronic Disease or Diabetes Mellitus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The overarching goal of this project is to leverage health information technology (HIT) to integrate available digital information on social needs to improve care for racial and ethnic minorities and socially disadvantaged populations with chronic diseases. In the previous phases of this project the investigators developed a social risk score to identify social needs among medically under-served patients with special emphasis on application among African American patients with low income and chronic diseases who face social determinants, risk factors, and needs (SDRN) challenges. The investigators also developed a clinical decision support (CDS) tool to present the social risk score to clinical providers and sought feedback from different users on the face and content validity of the CDS tool. In the current project the investigators will run a randomized clinical trial (RCT) study to pilot test the new risk score and CDS tool in selected primary care clinics at Johns Hopkins Health System (JHHS) and in collaboration with selected community-based organizations (CBOs). This system will help identify, manage, and refer patients with both high levels of disease burden and modifiable SDRN challenges.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Piloting a Clinical Decision Support Tool to Identify Patients With Social Needs and Provide Navigation Services and Referral to Community-Based Organizations: Protocol for a Randomized Controlled Trial.
Hatef E, Richards T, Topel K, Hail S, et al · · 2024 · cited 4× · PMID 39042426 · DOI 10.2196/57316 -
An Electronic Health Record-Based Platform for Social Needs Assessment and Navigation Services: Preliminary Results of an RCT.
Hatef E, Richards T, Hail S, Zhang T, et al · · 2025 · PMID 40475024 · DOI 10.1016/j.focus.2025.100344
Verify or expand the search:
- PubMed search for NCT05574699
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05574699 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 4 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05574699.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing