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NCT05564195: POCOR
Cognitive Trajectories After Surgery, a Clinical, Observational Feasibility Study
trial testing Postoperative cognitive function in Postoperative Cognitive Dysfunction in 24 participants. Completed in 4 October 2024.
4 October 2024
Quick facts
| Lead sponsor | Karolinska Institutet |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 24 |
| Start date | 10 January 2023 |
| Primary completion | 4 October 2024 |
| Estimated completion | 4 October 2024 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Postoperative cognitive function
Conditions studied
- Postoperative Cognitive Dysfunction — all drugs for Postoperative Cognitive Dysfunction →
Sponsor
Karolinska Institutet
Who can join
60 and older, any sex, with Postoperative Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Research problem and specific questions: Approximately 2.8 million surgeries are conducted yearly in Sweden and of these almost 50% are persons ≥ 60 years. Postoperative cognitive recovery is a concern for older persons. To date, there is no evidence for treating postoperative neurocognitive decline (POCD) and no assessment of cognitive function is routinely performed. The purpose is to is to test digital monitoring in clinical practice: I) test recruitment process and measure attrition rate; II) estimate the difference in main clinical outcomes (POCD) that will inform sample size calculations for the longitudinal observational mixed methods study, III) determine the usability and feasibility of digital monitoring. Participants: 50 patients ≥60 years undergoing inpatient surgery. Outcomes: depression, frailty, cognitive function, postoperative recovery and functional status .
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Usability and feasibility of a digital cognitive screening tool measuring older adults' early postoperative neurocognitive recovery: a protocol for a pilot study.
Amirpour A, Eckerblad J, Thorell A, Bergman L, et al · · 2023 · cited 4× · PMID 37479514 · DOI 10.1136/bmjopen-2022-070404 -
Evaluation of a Digital, Self-Administered, Cognitive Test Battery in Older Adult Patients Undergoing Abdominal Surgery: Nonrandomized Feasibility Trial.
Amirpour A, Saarijärvi M, Eckerblad J, Markovic G, et al · · 2025 · PMID 41202209 · DOI 10.2196/71911
Verify or expand the search:
- PubMed search for NCT05564195
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Postoperative Cognitive Dysfunction
Currently open trials in the same condition.
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- NCT06689137 — Effects of Dexmedetomidine on Postoperative Neurocognitive Disorder · active not recruiting
- NCT06658769 — Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly · NA · recruiting
Other Karolinska Institutet trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05564195 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
- Last refreshed: 12 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05564195.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing