NCT05558449 is a Phase 4 clinical trial of Hypnosedation in Foot Deformities, sponsored by University of Liege.

Who is sponsoring NCT05558449?

NCT05558449 is sponsored by University of Liege.

What drugs are being tested in NCT05558449?

Interventions in NCT05558449: Hypnosedation, Midazolam injection, Virtual reality.

What condition does NCT05558449 study?

NCT05558449 studies Foot Deformities, Regional Anesthesia Morbidity, Valgus; Hallux, Analgesia.

Is NCT05558449 still recruiting?

NCT05558449 is currently completed. Last updated 6 March 2024.

Last reviewed 2024-03-06 · How we verify

NCT05558449

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Virtual Reality Hypno-sedation on Functional Recovery and Anxiety in Foot Surgery With Regional Anesthesia

Completed Phase 4 Last updated 6 March 2024

What this trial tests

Phase 4 trial testing Hypnosedation in Foot Deformities in 57 participants. Completed in 16 October 2023.

Timeline

28 November 2022

Primary endpoint
16 October 2023

16 October 2023

Quick facts

Lead sponsor	University of Liege
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	57
Start date	28 November 2022
Primary completion	16 October 2023
Estimated completion	16 October 2023
Sites	1 location across Belgium

Drugs / interventions tested

Hypnosedation
Midazolam injection — full drug profile →
Virtual reality

Conditions studied

Foot Deformities — all drugs for Foot Deformities →
Regional Anesthesia Morbidity — all drugs for Regional Anesthesia Morbidity →
Valgus; Hallux — all drugs for Valgus; Hallux →
Analgesia — all drugs for Analgesia →

Sponsor

University of Liege

Who can join

18 and older, any sex, with Foot Deformities or Regional Anesthesia Morbidity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This prospective study aims to evaluate whether the implementation of a virtual reality hypnosedation (VRH)protocol reduces preoperative anxiety and increases patient comfort before, during, and after outpatient foot surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Influence of virtual reality with or without hypnosis on patient-related experience and functional recovery in outpatient foot surgery with regional anesthesia: a randomized controlled trial.
Carella M, Bicego A, Beck F, Malta C, et al · · 2025 · cited 1× · PMID 40545295 · DOI 10.1136/rapm-2025-106678

Verify or expand the search:

Other trials of Hypnosedation

Trials testing the same drug.

NCT03012399 — Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery · NA · active not recruiting

Other recruiting trials for Foot Deformities

Currently open trials in the same condition.

NCT05555459 — Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation · NA · recruiting

Other University of Liege trials

Trials by the same sponsor.

NCT07523178 — Effects of a Targeted Prevention Program on Change-of-Direction Biomechanics and Performance in Elite Female Soccer Play · NA · not yet recruiting
NCT07472400 — Mobility, Strength, and Functional Outcomes Before Surgery, at 3 Months, and at 6 Months After Hip Arthroscopy for Femor · not yet recruiting
NCT07331779 — Effect of tDCS Timing on Motor Recovery in Acute Stroke Rehabilitation · NA · not yet recruiting
NCT07237893 — Impact of a Physical Activity Intervention on Cardiometabolic Health, Mental Health, and Lifestyle Factors. · NA · not yet recruiting
NCT06964282 — Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthropl · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05558449 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Liege
Last refreshed: 6 March 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05558449.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing