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NCT05557669
Effect of Laparoscopic Cholecystectomy on Risk of Metabolic Syndrome
NA trial testing Laparoscopic cholecystectomy in Cholelithiasis in 400 participants. Status unknown.
30 March 2025
Quick facts
| Lead sponsor | Brothers Hospitallers Hospital in Cracow |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 400 |
| Start date | 17 February 2021 |
| Primary completion | 30 March 2025 |
| Estimated completion | 30 March 2025 |
| Sites | 1 location across Poland |
Drugs / interventions tested
- Laparoscopic cholecystectomy
Conditions studied
- Cholelithiasis — all drugs for Cholelithiasis →
- Metabolic Syndrome — all drugs for Metabolic Syndrome →
Sponsor
Brothers Hospitallers Hospital in Cracow
Who can join
Adults 18 to 75, any sex, with Cholelithiasis or Metabolic Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prospective cohort study. POPULATION: patients with gallstone disease qualified for laparoscopic cholecystectomy INTERVENTION: patients undergoing cholecystectomy for gallstones COMPARISON: gallstone disease without surgery in an observation period OUTCOME: metabolic syndrome symptoms evaluated in 3 months period The main inclusion criteria is cholelithiasis confirmed by ultrasound examination in patients between 18-75 years old. The main exclusion criteria are metabolic syndrome, diabetes, thyroid diseases, pancreatic diseases, serious abdominal surgeries in the past, pregnancy, and lactation. Participants who qualified for laparoscopic cholecystectomy in 3 months are included in the investigation group. Those not having cholecystectomy planned in the upcoming three months for any reason (no consent for surgery, long term) are included in the control group. The intervention is to assess all metabolic syndrome criteria (blood pressure, glucose tolerance, dyslipidemia, abdominal obesity) before and three months after surgery. The endpoint is to evaluate if the risk of metabolic syndrome after cholecystectomy is higher than in patients with gallstones.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
Verify or expand the search:
- PubMed search for NCT05557669
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other trials of Laparoscopic cholecystectomy
Trials testing the same drug.
- NCT07001423 — ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly · NA · recruiting
- NCT07119203 — Surgical Techniques: Robotic Versus Conventional Laparoscopic Cholecystectomy IN Benign Gallbladder Disease · NA · recruiting
- NCT07161960 — Early Versus Delayed Cholecystectomy After Percutaneous Cholecystostomy in Moderate and Severe Cholecystitis (ESCAPE) · NA · recruiting
- NCT06459323 — the Outcomes of Laparoscopic Cholecystectomy for Acute Cholecystitis Within and Beyond the First 72 Hours, Does it Diffe · NA · not yet recruiting
- NCT06685250 — Postoperative Pain After a Laparoscopic Cholecystectomy · NA · not yet recruiting
Other recruiting trials for Cholelithiasis
Currently open trials in the same condition.
- NCT07473687 — Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room · recruiting
- NCT07308730 — Pain Diary Use After Laparoscopic Cholecystectomy · NA · recruiting
- NCT07001423 — ChOlecystectomy aFter successFul Endoscopic Common Bile Duct Stone Extraction in Elderly · NA · recruiting
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- NCT07012772 — COMBO Endoscopy Oropharyngeal Airway in Sedated Endoscopic Retrograde Cholangiopancreatography for Patients · Phase 2 · recruiting
Other Brothers Hospitallers Hospital in Cracow trials
Trials by the same sponsor.
- NCT06530420 — The Usefulness of the New EHS/AHS Classification of Primary Umbilical Hernias in the Selection of Method of Their Treatm · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05557669 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Brothers Hospitallers Hospital in Cracow
- Last refreshed: 28 September 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05557669.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing